Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18055691 | 1.00 | TGFBR1 (0.44) | TGFBR1THRBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL5808266 | 1.00 | TGFBR1 (0.44) | TGFBR1THRBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL14409746 | 0.86 | THRB (0.50) | TGFBR1THRBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL14409743 | 0.84 | MME (0.41) | TGFBR1THRBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL12064041 | 0.84 | SMN1; SMN2 (0.45) | THRBSMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL12064029 | 0.84 | SMN1; SMN2 (0.45) | THRBSMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL12064309 | 0.84 | SMN1; SMN2 (0.45) | THRBSMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL6001470 | 0.83 | CAD (0.44) | TGFBR1THRBSMN1; SMN2KDM4EMAPT | |
| SCHEMBL5812827 | 0.83 | THRB (0.41) | THRBSMN1; SMN2KDM4EMAPTALOX15 | |
| SCHEMBL6001474 | 0.83 | CAD (0.44) | TGFBR1THRBSMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3144295-B1 | PROCESS FOR THE PREPARATION OF LACOSAMIDE | DIVIS LABORATORIES LTD (IN) | 2018-12-05 | — | — | EP | claimed |
| US-20060251597-A1 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J | 2006-11-09 | — | — | US | claimed |
| WO-2024026484-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026479-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
| CN-108047268-B | 1-aza-5-gera-5-alkyl bicyclo [3.3.3] undecane compound, synthesis method and application | 中国科学技术大学 | 2020-05-01 | — | — | CN | disclosed |
| WO-2017197014-A2 | COMPOSITIONS COMPRISING A POLYMERIC DYE AND A CYCLODEXTRIN AND USES THEREOF | SONY CORPORATION (JP) | 2017-11-16 | — | — | WO | disclosed |
| WO-2017173348-A1 | ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH RIGID SPACING GROUPS | SONY CORPORATION (JP) | 2017-10-05 | — | — | WO | disclosed |
| US-9447024-B1 | Process for the preparation of lacosamide | DIVI'S LABORATORIES LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| US-9447024-B1 | Process for the preparation of lacosamide | DIVI'S LABORATORIES LIMITED (IN) | 2016-09-20 | — | — | US | disclosed |
| US-9303059-B2 | Chemoselective enrichment for compound isolation | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-20150315227-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF COLORADO BOULDER | 2015-11-05 | — | — | US | disclosed |
| WO-2009004322-A2 | DERIVATIVES OF NYSTATIN AND THEIR USE AS ANTIFUNGAL AGENTS | BIOSERGEN AS (NO) | 2009-01-08 | — | — | WO | disclosed |
| WO-2006119283-A2 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J (US) | 2006-11-09 | — | — | WO | disclosed |
| US-20060251597-A1 | ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE | YU RUEY J | 2006-11-09 | — | — | US | disclosed |
| US-6569411-B2 | Deodoring, microbiocides, marking odors | THE GILLETTE COMPANY | 2003-05-27 | — | — | US | disclosed |
| US-20030018055-A1 | Serine carbonates | FRATER GEORGE (CH) | 2003-01-23 | — | — | US | disclosed |
| EP-1053223-A1 | SERINE CARBONATES | Givaudan SA (CH) | 2000-11-22 | — | — | EP | disclosed |
| WO-2000034232-A1 | SERINE CARBONATES | GIVAUDAN SA (CH) | 2000-06-15 | — | — | WO | disclosed |
| EP-1008587-A1 | Serine carbonates | Givaudan Roure (International) S.A. (CH) | 2000-06-14 | — | — | EP | disclosed |
| US-4670395-A | Enantioselective hydrolysis of N-acylamino acid esters using a combined enzyme system | THE STANDARD OIL COMPANY (US) | 1987-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018055-A1 | Serine carbonates | SRR, ME1, TASP1 | TGFBR1 2295/4885THRB 3849/4885SMN1; SMN2 1481/4885 |
| US-20150315227-A1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | POLN, POLRMT, NUDT21 | TGFBR1 4779/4885THRB 3823/4885SMN1; SMN2 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.