Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.44 |
| ▸ | RBP4 | P02753 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6071717 | 1.00 | TTR (0.46) | TTRAKR1C3SLC18A3RBP4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6071855 | 0.87 | SLC18A3 (0.45) | AKR1C3SLC18A3HTR1ADRD2DRD3 | |
| Trifluoroacetic Acid SCHEMBL6071920 | 0.85 | HSD11B1 (0.53) | RBP4TRPV1HSD11B1 | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.84 | SLC18A3 (0.62) | SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL6071612 | 0.81 | SLC18A3 (0.54) | SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL6071803 | 0.79 | KDM4E (0.45) | SLC18A3TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6071723 | 0.78 | ALDH1A1 (0.50) | SLC18A3HTR2A | |
| Trifluoroacetic Acid SCHEMBL6071817 | 0.78 | FAAH (0.43) | SLC18A3FAAH | |
| Trifluoroacetic Acid SCHEMBL6072334 | 0.77 | SLC18A3 (0.49) | AKR1C3SLC18A3 | |
| Trifluoroacetic Acid SCHEMBL6071622 | 0.77 | ALDH1A1 (0.44) | SLC18A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006071958-A1 | COMPOUNDS USEFUL AS CHEMOKINE RECEPTOR ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | WO | disclosed |