Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5814484 | 0.85 | TTR (0.46) | HSD11B1RBP4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6071717 | 0.85 | TTR (0.46) | HSD11B1RBP4TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6071817 | 0.83 | FAAH (0.43) | DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL6071803 | 0.82 | KDM4E (0.45) | GAADPP4DPP7TRPV1 | |
| Trifluoroacetic Acid SCHEMBL6072071 | 0.79 | SLC18A3 (0.62) | — | |
| Trifluoroacetic Acid SCHEMBL6071855 | 0.77 | SLC18A3 (0.45) | GAADPP4NPSR1 | |
| Trifluoroacetic Acid SCHEMBL6071718 | 0.77 | MAPT (0.52) | DPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL6072183 | 0.75 | GPR6 (0.50) | NPSR1 | |
| Trifluoroacetic Acid SCHEMBL6071612 | 0.75 | SLC18A3 (0.54) | — | |
| Trifluoroacetic Acid SCHEMBL6071723 | 0.74 | ALDH1A1 (0.50) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | MILLENNIUM PHARMACEUTICALS, INC. | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189628-A1 | Compounds useful as chemokine receptor antagonists | ACKR3, CCR5, CXCR2 | HSD11B1 785/4885EPHX2 544/4885GAA 3818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.