SCHEMBL5819166

SCHEMBL5819166

CC(=CC(=O)C=CN)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.35
CYP2C9 P11712 1/20 0.32
AKR1C3 P42330 1/20 0.31
PARP1 P09874 1/20 0.30
PARP15 Q460N3 1/20 0.30
PARP10 Q53GL7 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28872731 0.79 PTGS1 (0.39) PTGS1CYP2C9AKR1C3PARP1PARP15
SCHEMBL5710629 0.78 PTGS1 (0.37) PTGS1CYP2C9AKR1C3MAPT
SCHEMBL7778372 0.78 PTGS1 (0.37) PTGS1CYP2C9AKR1C3MAPT
SCHEMBL28227710 0.78 PTGS1 (0.37) PTGS1CYP2C9AKR1C3MAPT
SCHEMBL15362103 0.76 PTGS1 (0.35) PTGS1CYP2C9AKR1C3MAPT
SCHEMBL560356 0.70 ALDH1A1 (0.43) PTGS1CYP2C9AKR1C3MAPT
SCHEMBL11801788 0.70 ALDH1A1 (0.43) PTGS1CYP2C9AKR1C3MAPT
SCHEMBL9723870 0.69
SCHEMBL9723868 0.69
SCHEMBL4771428 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337664-A1 FRUIT FLY CONTROL MACQUARIE UNIVERSITY (AU) 2023-10-26 US claimed
EP-2612657-B1 ORODISPERSIBLE TABLET KYOWA KIRIN CO LTD (JP) 2023-08-09 EP claimed
US-20260041699-A1 FOSPROPOFOL FORMULATIONS EPALEX CORP (US) 2026-02-12 US disclosed
US-20250312361-A1 FOSPROPOFOL METHODS AND COMPOSITIONS EPALEX CORP (US) 2025-10-09 US disclosed
US-12397006-B2 Fospropofol formulations EPALEX CORPORATION (US) 2025-08-26 US disclosed
US-12377110-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2025-08-05 US disclosed
US-20230337664-A1 FRUIT FLY CONTROL MACQUARIE UNIVERSITY (AU) 2023-10-26 US disclosed
US-20230277567-A1 FOSPROPOFOL METHODS AND COMPOSITIONS EPALEX CORPORATION 2023-09-07 US disclosed
EP-2612657-B1 ORODISPERSIBLE TABLET KYOWA KIRIN CO LTD (JP) 2023-08-09 EP disclosed
US-20230172952-A1 Fospropofol Salts, Methods And Compositions EPALEX CORP (US) 2023-06-08 US disclosed
US-11628178-B2 Fospropofol methods and compositions EPALEX CORPORATION (US) 2023-04-18 US disclosed
EP-0643981-B1 A matrix for iontophoreses HISAMITSU PHARMACEUTICAL CO (JP) 2002-01-09 EP disclosed
US-6322550-B2 Method for transdermal administration of GP IIb/IIIa antagonist HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2001-11-27 US disclosed
EP-1138345-A2 A matrix for iontophoreses HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2001-10-04 EP disclosed
US-20010018568-A1 METHOD FOR TRANSDERMAL ADMINISTRATION OF GP IIB/IIIA ANTAGONIST HISAMITSU PHARMACEUTICAL CO., INC. (JP) 2001-08-30 US disclosed
EP-0950407-A1 Method for transdermal administration of GP IIb/IIIa antagonist Takeda Chemical Industries, Ltd. (JP) 1999-10-20 EP disclosed
EP-0575974-B1 Use of 24,25-dihydroxyvitamin D3 for the manufacture of a medicament for the treatment of rickets KUREHA CHEMICAL IND CO LTD (JP) 1997-01-08 EP disclosed
US-5508274-A SIDE EFFECT REDUCTION KUREHA CHEMICAL INDUSTRY COMPANY, LTD. (JP) 1996-04-16 US disclosed
EP-0643981-A1 A matrix for iontophoreses TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-03-22 EP disclosed
EP-0575974-A1 Use of 24,25-dihydroxyvitamin D3 for the manufacture of a medicament for the treatment of rickets KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1993-12-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11628178-B2 Fospropofol methods and compositions FOS, FOSB, PFAS PTGS1 1812/4885CYP2C9 69/4885AKR1C3 1791/4885
US-20230172952-A1 Fospropofol Salts, Methods And Compositions FOS, FOSB, SCN5A PTGS1 2265/4885CYP2C9 352/4885AKR1C3 1897/4885
US-20250312361-A1 FOSPROPOFOL METHODS AND COMPOSITIONS FOS, FOSB, PFAS PTGS1 1812/4885CYP2C9 69/4885AKR1C3 1791/4885
US-20230337664-A1 FRUIT FLY CONTROL NONO, HTR1D, TAS1R1 PTGS1 2832/4885CYP2C9 813/4885AKR1C3 3409/4885
US-20260041699-A1 FOSPROPOFOL FORMULATIONS FOS, PSEN1, FDPS PTGS1 2352/4885CYP2C9 182/4885AKR1C3 604/4885
US-20230277567-A1 FOSPROPOFOL METHODS AND COMPOSITIONS FOS, FOSB, PFAS PTGS1 1812/4885CYP2C9 69/4885AKR1C3 1791/4885
US-12397006-B2 Fospropofol formulations FOS, PFAS, FOSB PTGS1 4040/4885CYP2C9 93/4885AKR1C3 1328/4885
US-12377110-B2 Fospropofol methods and compositions FOS, FOSB, PFAS PTGS1 1812/4885CYP2C9 69/4885AKR1C3 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.