Sugi Predict

Sugi Predict / Compounds / SCHEMBL5820145

SCHEMBL5820145

SCHEMBL5820145

O=C(C(Br)c1ccccc1)C(Br)c1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CES2 O00748 3/20 0.73
▸ CES1 P23141 3/20 0.73
▸ SRC P12931 3/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ LMNA P02545 3/20 0.48
▸ MAPK1 P28482 1/20 0.48
▸ TDP1 Q9NUW8 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ HDAC3 O15379 1/20 0.43
▸ HDAC4 P56524 1/20 0.43
▸ HDAC1 Q13547 1/20 0.43
▸ HDAC7 Q8WUI4 1/20 0.43
▸ HDAC2 Q92769 1/20 0.43
▸ HDAC10 Q969S8 1/20 0.43
▸ HDAC11 Q96DB2 1/20 0.43
▸ HDAC8 Q9BY41 1/20 0.43
▸ HDAC6 Q9UBN7 1/20 0.43
▸ HDAC9 Q9UKV0 1/20 0.43
▸ HDAC5 Q9UQL6 1/20 0.43
▸ CTSD P07339 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28201061 0.86 CES2 (0.76) CES2CES1SRCCYP2D6LMNA
SCHEMBL5899350 0.86 CES2 (0.76) CES2CES1SRCCYP2D6LMNA
SCHEMBL604040 0.86 CES2 (0.76) CES2CES1SRCCYP2D6LMNA
SCHEMBL234580 0.86 CES2 (0.76) CES2CES1SRCCYP2D6LMNA
SCHEMBL11250368 0.86 CES2 (0.56) CES2CES1LMNA
SCHEMBL3529988 0.86 CES2 (0.61) CES2CES1SRCCYP2D6LMNA
Ammonia Solution, Strong SCHEMBL38660268 0.84 CES2 (0.73) CES2CES1SRCCYP2D6LMNA
Hydrochloric Acid SCHEMBL7037834 0.84 CES2 (0.73) CES2CES1SRCCYP2D6LMNA
Methane SCHEMBL6115781 0.84 CES2 (0.73) CES2CES1SRCCYP2D6LMNA
SCHEMBL6963982 0.82 CES2 (0.70) CES2CES1SRCCYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250238-B Cyclic-carbonyl-containing quaternary pentavalent phosphorus derivative, and synthesis method and catalytic application thereof 三峡大学 2021-01-26 — — CN claimed
CN-111808100-A Indole alkaloid compound and preparation method and application thereof 广州中医药大学(广州中医药研究院) 2020-10-23 — — CN claimed
EP-4386083-A1 METHOD FOR PRODUCING RENAL INTERSTITIAL PROGENITOR CELLS, ERYTHROPOIETIN-PRODUCING CELLS, AND METHOD FOR PRODUCING RENIN-PRODUCING CELLS Kyoto University (JP) 2024-06-19 — — EP disclosed
US-20240043811-A1 METHOD OF PRODUCING A MESODERMAL-LINEAGE PRIMITIVE STREAK CELL UNIV KYOTO (JP) 2024-02-08 — — US disclosed
US-11821007-B2 Method for inducing differentiation of intermediate mesodermal cell to renal progenitor cell, and method for inducing differentiation of pluripotent stem cell to renal progenitor cell KYOTO UNIVERSITY (JP) 2023-11-21 — — US disclosed
WO-2023017848-A1 METHOD FOR PRODUCING RENAL INTERSTITIAL PROGENITOR CELLS, ERYTHROPOIETIN-PRODUCING CELLS, AND METHOD FOR PRODUCING RENIN-PRODUCING CELLS 国立大学法人京都大学 2023-02-16 — — WO disclosed
CN-111757895-B Polymeric materials formed using initiators having a ketone group and two thiocarbonylthio groups 3M创新有限公司 2023-01-24 — — CN disclosed
CN-114804988-A Method for synthesizing brominated organic compound through oxygen oxidation bromination with controllable chemical selectivity 杭州医学院 2022-07-29 — — CN disclosed
US-11319461-B2 Polymeric materials formed using initiators with a ketone group and two thiocarbonylthio-containing groups 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-05-03 — — US disclosed
US-11225642-B2 Method for producing renal progenitor cells KYOTO UNIVERSITY (JP) 2022-01-18 — — US disclosed
US-20210332329-A1 NOVEL RENAL PROGENITOR CELL MARKER AND METHOD FOR CONCENTRATING RENAL PROGENITOR CELLS USING SAME KYOTO UNIVERSITY (JP) 2021-10-28 — — US disclosed
US-20030153751-A1 Inhibitors of phospholipase enzymes AMERICAN HOME PRODUCTS CORPORATION 2003-08-14 — — US disclosed
CN-1299347-A Inhibitor of phospholipase enzymes GENETICS INST (US) 2001-06-13 — — CN disclosed
CN-1298404-A Inhibitors of phospholipase A2 GENETICS INST (US) 2001-06-06 — — CN disclosed
EP-1062216-A1 INHIBITORS OF PHOSPHOLIPASE A2 GENETICS INSTITUTE, INC. (US) 2000-12-27 — — EP disclosed
EP-1056719-A2 INHIBITORS OF PHOSPHOLIPASE ENZYMES GENETICS INSTITUTE, INC. (US) 2000-12-06 — — EP disclosed
WO-1999043672-A9 INHIBITORS OF PHOSPHOLIPASE A2 GENETICS INST (US) 2000-05-04 — — WO disclosed
WO-1999043651-A2 INHIBITORS OF PHOSPHOLIPASE ENZYMES GENETICS INSTITUTE, INC. (US) 1999-09-02 — — WO disclosed
WO-1999043672-A1 INHIBITORS OF PHOSPHOLIPASE A2 GENETICS INSTITUTE, INC. (US) 1999-09-02 — — WO disclosed
US-3932338-A POLYOLEFINS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11319461-B2 Polymeric materials formed using initiators with a ketone group and two thiocarbonylthio-containing groups ESD, BHMT2, TST CES2 1020/4885CES1 2562/4885SRC 2814/4885
US-20030153751-A1 Inhibitors of phospholipase enzymes PLA2G4C, PLA2G4B, PLA2G4A CES2 298/4885CES1 116/4885SRC 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.