SCHEMBL58229

SCHEMBL58229

O=C(c1c(Cl)cccc1Cl)P(=O)(C(=O)c1c(Cl)cccc1Cl)c1ccc(Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.45
GAA P10253 4/20 0.43
HPGD P15428 2/20 0.38
JAK2 O60674 1/20 0.38
CYP3A4 P08684 1/20 0.38
JAK1 P23458 1/20 0.38
TYK2 P29597 1/20 0.38
ANO1 Q5XXA6 1/20 0.38
FEN1 P39748 1/20 0.37
P2RX7 Q99572 1/20 0.37
MAPT P10636 1/20 0.36
PTK2B Q14289 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NPC1 O15118 1/20 0.36
GLA P06280 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
DOT1L Q8TEK3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL58730 0.87 ALDH1A1 (0.47) ALDH1A1HPGDJAK2CYP3A4JAK1
SCHEMBL2770598 0.84 MEN1 (0.47) ALDH1A1HPGDFEN1MAPTPTK2B
SCHEMBL7183633 0.83 ALDH1A1 (0.40) ALDH1A1GAAJAK2TYK2FEN1
SCHEMBL7642524 0.82 RAB9A (0.51) ALDH1A1GAAMAPTRAB9ASMN1; SMN2
SCHEMBL7179365 0.81 ALDH1A1 (0.41) ALDH1A1HPGDJAK2CYP3A4JAK1
SCHEMBL7189823 0.80 TSHR (0.41) ALDH1A1HPGDJAK2CYP3A4JAK1
SCHEMBL57873 0.79 GAA (0.43) ALDH1A1GAAMAPTRAB9ASMN1; SMN2
SCHEMBL29040901 0.78 POLB (0.41) ALDH1A1HPGDMAPTRAB9ASMN1; SMN2
SCHEMBL7179862 0.78 TYK2 (0.44) ALDH1A1GAATYK2MAPTPTK2B
SCHEMBL7188901 0.78 ALDH1A1 (0.39) ALDH1A1GAAHPGDCYP3A4TYK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4506424-A1 RADIATION-CURABLE COMPOSITION Marabu GmbH & Co. KG (DE) 2025-02-12 EP claimed
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4056658-A1 RADIATION-CURABLE COMPOUND Marabu GmbH & Co. KG (DE) 2022-09-14 EP claimed
EP-4286163-B1 ELECTRON BEAM CURABLE INK, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2026-04-01 EP disclosed
US-12577340-B2 Storage stable two-component dual cure dental composition SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-17 US disclosed
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-01-29 US disclosed
EP-4681930-A1 IMAGE RECORDING METHOD, METHOD FOR MANUFACTURING LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM Corporation (JP) 2026-01-21 EP disclosed
US-20250375971-A1 IMAGE RECORDING METHOD, MANUFACTURING METHOD OF LAMINATE, AND IMAGE RECORDING APPARATUS FUJIFILM CORP (JP) 2025-12-11 US disclosed
EP-4660262-A1 ACTIVE ENERGY RAY-CURABLE INKJET INK, ACTIVE ENERGY RAY-CURABLE INK SET, AND IMAGE RECORDING METHOD FUJIFILM Corporation (JP) 2025-12-10 EP disclosed
US-20250340747-A1 ACTIVE ENERGY RAY CURABLE TYPE INK JET INK, ACTIVE ENERGY RAY CURABLE TYPE INK SET, AND IMAGE RECORDING METHOD FUJIFILM CORP (JP) 2025-11-06 US disclosed
EP-4629958-A1 SURFACE-TREATED FILLER, DENTAL COMPOSITION CONTAINING SUCH A FILLER, PROCESS OF PRODUCTION AND USE THEREOF Solventum Intellectual Properties Company (US) 2025-10-15 EP disclosed
EP-0825201-B2 Photocurable composition and curing process therefor SHOWA DENKO KK (JP) 2006-11-29 EP disclosed
US-20050221210-A1 Electrophotographic photoconductor and image formation method, image formation apparatus, and process cartridge for image formation apparatus using the electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2005-10-06 US disclosed
EP-0825201-B1 Photocurable composition and curing process therefor SHOWA DENKO KK (JP) 2002-02-27 EP disclosed
US-20020022130-A1 UV-curable binder composition for magnetic recording media and photoinitiator mixture EMTEC MAGNETICS GMBH (DE) 2002-02-21 US disclosed
EP-1044777-A1 Molding method for corrosion-resistant FRP SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-10-18 EP disclosed
EP-0825201-A1 Photocurable composition and curing process therefor SHOWA DENKO KABUSHIKI KAISHA (JP) 1998-02-25 EP disclosed
US-4868091-A USING A BISACYLPHOSPHINE OXIDE PHOTOINITIATOR, UNSATURATED COMPOUND AND POLYMERIC BINDER; SHORT EXPOSURE TIME; NEWSPAPER PRINTING BASF AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028440-A1 Curable Composition for Producing Transparent Orthodontic Attachments SMCHD1, SMC2, SMC1A ALDH1A1 1413/4885GAA 1471/4885HPGD 4304/4885
US-12577340-B2 Storage stable two-component dual cure dental composition GPX4, SSRP1, H1-0 ALDH1A1 93/4885GAA 2835/4885HPGD 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.