Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8743897 | 0.98 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7507608 | 0.93 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7634908 | 0.89 | THRB (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL5832449 | 0.86 | TSHR (0.51) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL64810 | 0.86 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8048856 | 0.85 | TSHR (0.44) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL64556 | 0.84 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26561519 | 0.84 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL143449 | 0.84 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL7758879 | 0.83 | ALDH1A1 (0.50) | TSHRHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3257685-B1 | LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MANUFACTURING SAME, AND PRINTING METHOD USING SAME | FUJIFILM CORP (JP) | 2020-03-04 | — | — | EP | disclosed |
| US-10022998-B2 | Planographic printing plate precursor, method of producing same, and printing method using same | FUJIFILM CORPORATION (JP) | 2018-07-17 | — | — | US | disclosed |
| EP-3257685-A1 | LITHOGRAPHIC PRINTING ORIGINAL PLATE, METHOD FOR MANUFACTURING SAME, AND PRINTING METHOD USING SAME | Fujifilm Corporation (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-20170320350-A1 | PLANOGRAPHIC PRINTING PLATE PRECURSOR, METHOD OF PRODUCING SAME, AND PRINTING METHOD USING SAME | FUJIFILM CORPORATION (JP) | 2017-11-09 | — | — | US | disclosed |
| US-7030259-B2 | Process for the preparation of silicone compounds | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20050256330-A1 | Process for the preparation of silicone compounds | DOW TORAY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1472264-B1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | DOW CORNING TORAY SILICONE (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1472264-A1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | Dow Corning Toray Silicone Co., Ltd. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003064436-A1 | PROCESSES FOR THE PREPARATION OF SILICONE COMPOUNDS | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2003-08-07 | — | — | WO | disclosed |
| US-6399212-B1 | COATINGS WITH ORGANOSILICON COMPOUNDS AND SOLUTION OF SILICOFLUORIC ACID AND SILICON DIOXIDE | NIPPON SHEET GLASS CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| EP-0753521-B1 | Process for distilling crude acrylic silane solution | CHISSO CORP (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |
| CN-1293216-A | Polyolefinic resin for coating silicon dioxide and its preparation method | NIPPON SHEET GLASS CO LTD (JP) | 2001-05-02 | — | — | CN | disclosed |
| EP-1094090-A2 | Silicon dioxide-coated polyolefin resin and process for its production | NIPPON SHEET GLASS CO. LTD. (JP) | 2001-04-25 | — | — | EP | disclosed |
| US-6063887-A | 1-acyloxy-organotetrasiloxane and production method for the preparation of the same | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5856545-A | Method for preparation of organopentasiloxane | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| US-5824195-A | USING N-NITROSOPHENYLHYDROXYLAMINE SALT AND/OR COPPER DIALKYLDITHIOCARBAMATE SYNERGISTIC MIXTURE AS POLYMERIZATION INHIBITORS | CHISSO CORPORATION (JP) | 1998-10-20 | — | — | US | disclosed |
| US-4202812-A | CURED ELASTOMERS WITH IMPROVED TENSILE STRENGTH | DOW CORNING CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256330-A1 | Process for the preparation of silicone compounds | ADH1C, ACMSD, SORD | TSHR 3154/4885THRB 2635/4885POLB 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.