Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 5/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833112 | 0.82 | ROCK2 (0.41) | ACHECHRM2CHRM3 | |
| SCHEMBL5833278 | 0.81 | RNF4 (0.42) | ACHECHRM2CHRM3 | |
| SCHEMBL5833539 | 0.81 | CHRM2 (0.47) | SIGMAR1CHRM2CHRM3 | |
| SCHEMBL5833452 | 0.80 | DCUN1D1 (0.40) | SIGMAR1MEN1KMT2AACHE | |
| SCHEMBL5833435 | 0.80 | SIGMAR1 (0.42) | SIGMAR1MEN1KMT2AACHEBCHE | |
| SCHEMBL5833937 | 0.80 | OPRD1 (0.47) | KMT2AACHECHRM2CHRM3 | |
| SCHEMBL4244062 | 0.78 | SIGMAR1 (0.48) | SIGMAR1ACHECHRM3 | |
| SCHEMBL5832943 | 0.77 | ALPL (0.54) | SIGMAR1MEN1KMT2AACHEBCHE | |
| SCHEMBL5833269 | 0.77 | KDM1A (0.40) | MEN1KMT2A | |
| SCHEMBL5833024 | 0.77 | BRD4 (0.38) | SIGMAR1MEN1KMT2ACHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008955-B2 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | claimed |