Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.40 |
| ▸ | UBE2M | P61081 | 6/20 | 0.40 |
| ▸ | TACR1 | P25103 | 4/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | GRK5 | P34947 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5833112 | 0.84 | ROCK2 (0.41) | ACHE | |
| SCHEMBL5833539 | 0.82 | CHRM2 (0.47) | SIGMAR1 | |
| SCHEMBL5833278 | 0.81 | RNF4 (0.42) | ACHE | |
| SCHEMBL5833430 | 0.80 | SIGMAR1 (0.43) | SIGMAR1ACHEMEN1KMT2A | |
| SCHEMBL5833937 | 0.79 | OPRD1 (0.47) | ACHEKMT2A | |
| SCHEMBL5833269 | 0.78 | KDM1A (0.40) | DCUN1D1MEN1KMT2A | |
| SCHEMBL5844904 | 0.78 | LMNA (0.38) | DCUN1D1UBE2MSIGMAR1ACHEMEN1 | |
| SCHEMBL5833024 | 0.78 | BRD4 (0.38) | SIGMAR1MEN1KMT2A | |
| SCHEMBL5833447 | 0.78 | TACR1 (0.41) | TACR1TACR2KCNH2MEN1KMT2A | |
| SCHEMBL5833003 | 0.75 | SIGMAR1 (0.41) | SIGMAR1ACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7008955-B2 | (2-azabicyclo[2.2.1]hept-7yl) methanol derivatives as nicotinic acetylcholine receptor agonists | MERCK PATENT GMBH (DE) | 2006-03-07 | — | — | US | claimed |