SCHEMBL5833685

SCHEMBL5833685

C=CC(=O)NN1CC(C)C(=O)C1=O

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8418547 0.73 PIK3CD (0.34)
SCHEMBL11161329 0.73
SCHEMBL30695265 0.66 TGM2 (0.34) TSHR
SCHEMBL6348530 0.63 LMNA (0.36) TSHR
SCHEMBL9420472 0.63 ALDH1A1 (0.37) TSHR
SCHEMBL4120737 0.63 TSHR (0.40) TSHR
SCHEMBL974246 0.62 FGFR4 (0.35) TSHR
SCHEMBL27917088 0.62 TGM2 (0.38) TSHR
SCHEMBL23581934 0.61 ALDH1A1 (0.40) TSHR
SCHEMBL28602531 0.61 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6991781-B2 Delivery of reactive agents via bi-layer structures for use in shelf-stable products THE PROCTER & GAMBLE COMPANY (US) 2006-01-31 US disclosed
US-6936264-B2 Delivery of reactive agents via multiple emulsions for use in shelf stable products THE PROCTER & GAMBLE COMPANY (US) 2005-08-30 US disclosed
EP-1392221-A2 DELIVERY OF REACTIVE AGENTS VIA MULTIPLE EMULSIONS FOR USE IN SHELF STABLE PRODUCTS The Procter & Gamble Company (US) 2004-03-03 EP disclosed
US-20020155080-A1 Delivery of reactive agents via multiple emulsions for use in shelf stable products PROCTER & GAMBLE COMPANY, THE 2002-10-24 US disclosed
US-20020131944-A1 Delivery of reactive agents via bi-layer structures for use in shelf-stable products PROCTER & GAMBLE COMPANY, THE 2002-09-19 US disclosed
WO-2002069917-A2 DELIVERY OF REACTIVE AGENTS VIA MULTIPLE EMULSIONS FOR USE IN SHELF STABLE PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2002-09-12 WO disclosed
US-4859460-A REACTING HAIR WITH REDUCING AGENT THEN POLYHALOACETYLATED POLYMER SOCIETE ANONYME DITE L'OREAL (FR) 1989-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020131944-A1 Delivery of reactive agents via bi-layer structures for use in shelf-stable products TYR, LPO, ABAT TSHR 2775/4885
US-20020155080-A1 Delivery of reactive agents via multiple emulsions for use in shelf stable products POLR1C, IMMT, NACA TSHR 2592/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.