Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.36 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.36 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.36 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.36 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.36 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.36 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.36 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.36 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.36 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288225 | 0.74 | ACHE (0.46) | ALDH1A1GAAHPGDACHETUBB4A | |
| SCHEMBL4065639 | 0.74 | TRPV4 (0.53) | TRPV4ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL8764001 | 0.73 | TRPV4 (0.43) | TRPV4ALDH1A1KDM4EHPGDTUBB4A | |
| SCHEMBL11655127 | 0.73 | EPHX2 (0.43) | TRPV4ALDH1A1ACHETUBB4ATUBB | |
| SCHEMBL881433 | 0.73 | ERN1 (0.40) | ALDH1A1KDM4EHPGDACHETUBB4A | |
| SCHEMBL12653142 | 0.71 | ACHE (0.48) | ALDH1A1KDM4EGAAHPGDACHE | |
| SCHEMBL4469024 | 0.71 | ALDH1A1 (0.42) | TRPV4ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL2368094 | 0.71 | CA9 (0.49) | TRPV4ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL5835958 | 0.69 | TRPV4 (0.56) | TRPV4ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL2325686 | 0.69 | CA1 (0.41) | TRPV4ALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7026349-B2 | Sulfonamides | SMITHKLINE BEECHAM CORPORATION (US) | 2006-04-11 | — | — | US | disclosed |