SCHEMBL445024

SCHEMBL445024

Cc1ccc(/N=C/c2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
CA2 P00918 4/20 0.58
CA1 P00915 3/20 0.58
PTGS2 P35354 6/20 0.56
CA12 O43570 2/20 0.56
CA9 Q16790 2/20 0.56
PTGS1 P23219 2/20 0.56
L3MBTL1 Q9Y468 4/20 0.53
KDM4E B2RXH2 3/20 0.53
GLA P06280 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.49
MAPT P10636 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NPSR1 Q6W5P4 2/20 0.49
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
GAA P10253 2/20 0.49
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL445025 1.00 ALDH1A1 (0.61) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL443279 0.91 ALDH1A1 (0.63) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL443280 0.91 ALDH1A1 (0.63) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL12633723 0.89 ALDH1A1 (0.74) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL20186922 0.89 ALDH1A1 (0.74) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL11588746 0.89 ALDH1A1 (0.74) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL11557679 0.89 ALDH1A1 (0.74) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL255410 0.89 ALDH1A1 (0.74) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL3417678 0.89 CA2 (0.69) ALDH1A1CA2CA1PTGS2CA12
SCHEMBL3417682 0.89 CA2 (0.69) ALDH1A1CA2CA1PTGS2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO claimed
CN-116640415-A Recyclable epoxy resin, system material, composite material and recycling method thereof 道生天合材料科技(上海)股份有限公司 2023-08-25 CN claimed
CN-102399118-A Metal amino borane compound and application of derivative thereof in reduction reaction DALIAN CHEMICAL PHYSICS INST 2012-04-04 CN claimed
US-20120065430-A1 Application of Metal Amidoborane and Their Derivatives in Reduction Reaction DALIAN INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) 2012-03-15 US claimed
US-4176198-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1979-11-27 US claimed
CN-119303575-A Novel Cu+Zr (OH)4Application of physical mixed catalyst in catalytic synthesis of N-benzylidene aniline or derivative thereof 兰州大学 2025-01-14 CN disclosed
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO disclosed
US-11891408-B2 Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane SOOCHOW UNIVERSITY (CN) 2024-02-06 US disclosed
US-11845068-B2 Use of n-butyllithium for catalyzing hydroboration of imine and borane SOOCHOW UNIVERSITY (CN) 2023-12-19 US disclosed
CN-116640415-A Recyclable epoxy resin, system material, composite material and recycling method thereof 道生天合材料科技(上海)股份有限公司 2023-08-25 CN disclosed
US-11680075-B2 Application of 4-MePhNHLi in catalyzing hydroboration reaction of imine and borane SOOCHOW UNIVERSITY (CN) 2023-06-20 US disclosed
US-20210220808-A1 USE OF N-BUTYLLITHIUM FOR CATALYZING HYDROBORATION OF IMINE AND BORANE SOOCHOW UNIVERSITY (CN) 2021-07-22 US disclosed
US-5431697-A Reversibly variable color patterning composition for synthetic resin articles MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1995-07-11 US disclosed
US-5221288-A Treating cellulose fiber textile product with cationic compound, immersing in dispersion of microencapsulated thermochromic or photochromic material MATSUI SHIKISO CHEMICAL CO., LTD. (JP) 1993-06-22 US disclosed
EP-0480162-A1 Dyeing method and dyed product MATSUI SHIKISO CHEMICAL CO., LTD (JP) 1992-04-15 EP disclosed
US-4235929-A TOPICAL ADMINISTRATION OF ANTIINFLAMMATORY AGENT WILLIAM H. RORER, INC. (US) 1980-11-25 US disclosed
US-4230727-A N-BENZYLIDENEANILINE AND DERIVATIVES WILLIAM H. RORER, INC. (US) 1980-10-28 US disclosed
US-4198349-A ANTIINFLAMMATORY, TOPICAL WILLIAM H. RORER, INC. (US) 1980-04-15 US disclosed
US-4187317-A Sunscreen and erythema treating with N-benzylidene anilenes WILLIAM H. RORER, INC. (US) 1980-02-05 US disclosed
US-4176198-A ANTIINFLAMMATORY AGENTS WILLIAM H. RORER, INC. (US) 1979-11-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680075-B2 Application of 4-MePhNHLi in catalyzing hydroboration reaction of imine and borane HRH4, HRH3, HRH1 ALDH1A1 2372/4885CA2 914/4885CA1 2737/4885
US-20210220808-A1 USE OF N-BUTYLLITHIUM FOR CATALYZING HYDROBORATION OF IMINE AND BORANE INMT, SLC6A12, ICMT ALDH1A1 4186/4885CA2 1390/4885CA1 2910/4885
US-11845068-B2 Use of n-butyllithium for catalyzing hydroboration of imine and borane INMT, SLC6A12, ICMT ALDH1A1 4186/4885CA2 1390/4885CA1 2910/4885
US-11891408-B2 Application of lithium 4-methoxyaniline in catalysis of hydroboration reaction of imine and borane ME1, MCM4, INMT ALDH1A1 3287/4885CA2 570/4885CA1 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.