Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 2,4-Dichlorophenoxyacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.70 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL29364305 | 1.00 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL569391 | 1.00 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL8645275 | 0.98 | TDP1 (0.68) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4587469 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4588342 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL4586667 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL28782065 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL2400880 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL13571537 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL28782052 | 0.97 | TDP1 (0.70) | TDP1TSHRSMN1; SMN2HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 310 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3768763-B1 | SILICONE POLYMER AND COMPOSITION COMPRISING THE SAME | MOMENTIVE PERFORMANCE MAT INC (US) | 2026-04-29 | — | — | EP | claimed |
| US-20240334928-A1 | COMPOSITIONS WITH MICROENCAPSULATED ACETAMIDE AND METAL-CHELATED MESOTRIONE | MONSANTO TECHNOLOGY LLC | 2024-10-10 | — | — | US | claimed |
| CN-116120168-B | Preparation process for catalytic synthesis of 2, 4-D | 湖北泰盛化工有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-115581235-B | Weeding composition and application thereof | 允发化工（上海）有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117902971-A | Preparation method for synthesizing 2, 4-dichlorophenoxyacetic acid by composite molecular sieve ZSM-5 catalysis and applying water reducing process | 湖北泰盛化工有限公司 | 2024-04-19 | — | — | CN | claimed |
| CN-114085849-B | Herbicide resistance protein, gene and use | 青岛清原种子科学有限公司 | 2024-03-29 | — | — | CN | claimed |
| WO-2024060737-A1 | PREPARATION PROCESS FOR CATALYTIC SYNTHESIS OF 2,4-DICHLOROPHENOXYACETIC ACID | 湖北泰盛化工有限公司 | 2024-03-28 | — | — | WO | claimed |
| EP-4337017-A1 | HERBICIDE/SAFENER COMBINATION BASED ON SAFENERS FROM THE CLASS OF SUBSTITUTED [(1,5-DIPHENYL-1H-1,2,4-TRIAZOL-3-YL)OXY]ACETIC ACIDS AND THEIR SALTS | Bayer Aktiengesellschaft (DE) | 2024-03-20 | — | — | EP | claimed |
| CN-117342542-A | High-capacity porous hard carbon composite material and preparation method and application thereof | 常州烯源谷新材料科技有限公司 | 2024-01-05 | — | — | CN | claimed |
| EP-3491097-B1 | AN ORGANOCLAY COMPOSITION AND ITS USE | BYK CHEMIE GMBH (DE) | 2023-10-04 | — | — | EP | claimed |
| EP-1152744-B1 | SKIN SANITIZING COMPOSITIONS | PROCTER & GAMBLE (US) | 2004-08-18 | — | — | EP | claimed |
| US-5866514-A | HIGH BOILING; ODORLESS; ANTISEPTICS, HERBICIES, INSECTICIDES | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1999-02-02 | — | — | US | claimed |
| EP-0876098-A2 | LIGNIN-BASEDPEST CONTROL FORMULATIONS | THE UNITED STATES OF AMERICA, represented by THE SECRETARY OF THE DEPARTMENT OF AGRICULTURE (US) | 1998-11-11 | — | — | EP | claimed |
| US-5750467-A | WON'T WASH OFF, ULTRAVIOLET STABLE | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1998-05-12 | — | — | US | claimed |
| WO-1997020462-A2 | LIGNIN-BASEDPEST CONTROL FORMULATIONS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1997-06-12 | — | — | WO | claimed |
| EP-0127945-B1 | A COMPOSITION FOR REGULATING PLANT GROWTH | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-01-17 | — | — | EP | claimed |
| US-4755214-A | Composition for regulating plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-07-05 | — | — | US | claimed |
| EP-0127945-A2 | A composition for regulating plant growth | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | claimed |
| US-4344857-A | Encapsulation by entrapment | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1982-08-17 | — | — | US | claimed |
| US-4277364-A | Encapsulation by entrapment | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1981-07-07 | — | — | US | claimed |