Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770781 | 0.82 | CA2 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL29137248 | 0.82 | ALDH1A1 (0.55) | ALDH1A1PLK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL711848 | 0.80 | PLOD2 (0.50) | NPC1RAB9AMLYCD | |
| SCHEMBL5865895 | 0.80 | MLYCD (0.59) | ALDH1A1PLK1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL583454 | 0.79 | CES1 (0.43) | LMNAMLYCDTDP1HPGDHDAC4 | |
| SCHEMBL584064 | 0.79 | CES2 (0.43) | ALDH1A1RAB9ACYP1A2CYP2C19LMNA | |
| SCHEMBL583437 | 0.78 | CES1 (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL709888 | 0.78 | CES2 (0.48) | ALDH1A1PLK1LMNATDP1GAA | |
| SCHEMBL9630805 | 0.77 | CES1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL9655468 | 0.77 | CES1 (0.55) | ALDH1A1SMN1; SMN2NPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289390-B1 | PROCESS FOR ELIMINATING RADIOACTIVITY FROM EFFLUENTS BY LIQUID-LIQUID EXTRACTION | RHONE-POULENC CHIMIE (FR) | 1991-10-16 | — | — | EP | disclosed |
| US-5006254-A | Extraction with halogenated beta-diketone | RHONE-POULENC CHIMIE (FR) | 1991-04-09 | — | — | US | disclosed |
| EP-0289390-A1 | Process for eliminating radioactivity from effluents by liquid-liquid extraction | RHONE-POULENC CHIMIE (FR) | 1988-11-02 | — | — | EP | disclosed |