Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5012151 | 0.80 | FAAH (0.61) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL2260845 | 0.80 | MCL1 (0.70) | MCL1CYP2C9GAAALDH1A1POLB | |
| SCHEMBL3704245 | 0.78 | L3MBTL1 (0.56) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL23135844 | 0.77 | FAAH (0.54) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL17515328 | 0.77 | HPGD (0.57) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL2632301 | 0.76 | ALDH1A1 (0.57) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL625919 | 0.76 | CYP2C9 (0.61) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL29811285 | 0.76 | ALDH1A1 (0.57) | FAAHL3MBTL1NAMPTCYP2C9KDM4E | |
| SCHEMBL9188646 | 0.76 | ALDH1A1 (0.53) | ALDH1A1 | |
| SCHEMBL2264470 | 0.76 | MCL1 (0.59) | MCL1KDM4EMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020249821-A1 | NOVEL ARGINASE INHIBITORS | RIJKSUNIVERSITEIT GRONINGEN (NL) | 2020-12-17 | — | — | WO | disclosed |
| US-7153815-B2 | Insecticide containing hydrazone derivative as the active ingredient and novel hydrazone derivative | NIHON NOHYAKU CO., LTD. (JP) | 2006-12-26 | — | — | US | disclosed |
| US-20050203149-A1 | Insecticide containing hydrazone derivatives as the active ingredient and novel hydrazone derivates | NIHON NOHYAKU CO., LTD (JP) | 2005-09-15 | — | — | US | disclosed |
| EP-1470752-A1 | INSECTICIDES CONTAINING HYDRAZONE DERIVATIVES AS THE ACTIVE INGREDIENT AND NOVEL HYDRAZONE DERIVATIVES | Nihon Nohyaku Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050203149-A1 | Insecticide containing hydrazone derivatives as the active ingredient and novel hydrazone derivates | DDT, AOX1, HAX1 | MCL1 4560/4885FAAH 239/4885L3MBTL1 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.