Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541634 | 0.92 | ALDH1A1 (0.60) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL257112 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL10261585 | 0.85 | ALDH1A1 (0.53) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL17485847 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL6999435 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL4140284 | 0.83 | ALDH1A1 (0.51) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL3974470 | 0.81 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL29141709 | 0.81 | TDP1 (0.46) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL28045560 | 0.80 | ELANE (0.46) | ALDH1A1TDP1SMN1; SMN2HPGDNPC1 | |
| SCHEMBL19220827 | 0.80 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989094-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | Archer Daniels Midland Company (US) | 2016-03-02 | — | — | EP | claimed |
| US-20160052902-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | ARCHER DANIELS MIDLAND CO (US) | 2016-02-25 | — | — | US | claimed |
| WO-2014175989-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-10-30 | — | — | WO | claimed |
| US-20170226075-A1 | Synthesis of Non-Ionic Surfactants From 5-Hydroxymethyl-2-Furfural, Furan-2,5-Dimethanol and Bis-2,5-Dihydroxymethyl-Tetrahydrofurans | ARCHER DANIELS MIDLAND CO (US) | 2017-08-10 | — | — | US | disclosed |
| EP-2989094-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | Archer Daniels Midland Company (US) | 2016-03-02 | — | — | EP | disclosed |
| US-20160052902-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | ARCHER DANIELS MIDLAND CO (US) | 2016-02-25 | — | — | US | disclosed |
| WO-2014175989-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-10-30 | — | — | WO | disclosed |
| WO-2014175989-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | ARCHER DANIELS MIDLAND COMPANY (US) | 2014-10-30 | — | — | WO | disclosed |
| US-RE39199-E1 | Antipsoriatic compositions, method of making, and method of using | MOADY NASEBA | 2006-07-18 | — | — | US | disclosed |
| EP-1166791-A2 | Antipsoriatic compositions comprising an asphodelus extract, method of making, and method of using | Moady, Said (US) | 2002-01-02 | — | — | EP | disclosed |
| US-5852060-A | Antipsoriatic compositions, method of making, and method of using | MOADY MARZOOK (US) | 1998-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226075-A1 | Synthesis of Non-Ionic Surfactants From 5-Hydroxymethyl-2-Furfural, Furan-2,5-Dimethanol and Bis-2,5-Dihydroxymethyl-Tetrahydrofurans | MTHFD2, DHFR, DHPS | ALDH1A1 2080/4885TDP1 748/4885SMN1; SMN2 3104/4885 |
| US-20160052902-A1 | CATALYTIC SYNTHESIS OF REDUCED FURAN DERIVATIVES | ADH5, FASN, ADH1C | ALDH1A1 45/4885TDP1 2801/4885SMN1; SMN2 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.