Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 3/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5859192 | 0.90 | PSMD14 (0.51) | MAPTMEN1KMT2ALMNAABL1 | |
| SCHEMBL6661408 | 0.89 | GPR27 (0.44) | LMNASMN1; SMN2NPSR1NPC1GMNN | |
| SCHEMBL5859923 | 0.86 | MAPT (0.49) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5859896 | 0.81 | MKNK1 (0.39) | LMNAHTTDHODH | |
| SCHEMBL5860306 | 0.80 | SMO (0.44) | MAPTLMNASMN1; SMN2NPSR1TRPV1 | |
| SCHEMBL5859178 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5859917 | 0.78 | MAPT (0.48) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL5860337 | 0.77 | APOB (0.44) | TRPV1 | |
| SCHEMBL5860145 | 0.76 | BRAF (0.49) | MAPTMEN1KMT2ALMNAABL1 | |
| SCHEMBL5859955 | 0.74 | CYP2C9 (0.43) | MEN1KMT2ASMN1; SMN2ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7122543-B2 | Substituted benzoic acid derivatives having NF-κB inhibiting action | DAIICHI SUNTORY PHARMA CO., LTD. (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1437339-A1 | SUBSTITUTED BENZOIC ACID DERIVATIVES EXHIBITING NF-KAPPA B INHIBITING ACTIVITY | Daiichi Suntory Pharma Co., Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |