Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 7/20 | 0.57 |
| ▸ | HTR1A | P08908 | 6/20 | 0.57 |
| ▸ | HTR2A | P28223 | 6/20 | 0.57 |
| ▸ | HRH1 | P35367 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.57 |
| ▸ | HTR6 | P50406 | 4/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.57 |
| ▸ | DRD5 | P21918 | 3/20 | 0.57 |
| ▸ | HRH2 | P25021 | 3/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864444 | 0.86 | CYP3A4 (0.55) | DRD4HTR1AHTR2AHRH1DRD3 | |
| Fumaric Acid SCHEMBL9601877 | 0.81 | DRD4 (0.60) | DRD4HTR1AHTR2AHRH1DRD3 | |
| Fumaric Acid SCHEMBL9601866 | 0.81 | DRD4 (0.60) | DRD4HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL2951878 | 0.80 | ALDH1A1 (0.66) | HTR1ATSHRMAPK1RAB9AMEN1 | |
| SCHEMBL4750789 | 0.79 | SLC6A3 (0.64) | DRD4HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL5864261 | 0.79 | ENPP2 (0.55) | HTR1ASLC6A3MEN1KMT2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL10810457 | 0.78 | MEN1 (0.72) | DRD4HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL5863501 | 0.78 | SLC6A9 (0.45) | DRD4HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL10362364 | 0.77 | HTR2A (0.61) | DRD4HTR1AHTR2AHRH1DRD3 | |
| SCHEMBL1663641 | 0.77 | DRD2 (0.54) | DRD4HTR1AHTR2AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030120-B2 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-04-18 | — | — | US | disclosed |
| US-20040224959-A1 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | OHKURA NAOTO (JP) | 2004-11-11 | — | — | US | disclosed |
| US-6777414-B1 | INHIBITORS OF TRIGLYCERIDE BIOSYNTHESIS AND SECRETION OF APOLIPOPROTEIN B-CONTAINING LIPOPROTEINS; ARTERIOSCLEROTIC DISEASES; HYPERLIPIDEMIA | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-08-17 | — | — | US | disclosed |
| EP-1180514-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND BENAMIDE COMPOUNDS AND DRUGS CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 2002-02-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224959-A1 | Nitrogen-containing heterocyclic compounds and benzamide compounds and drugs containing the same | APOB, NCEH1, LIPC | DRD4 599/4885HTR1A 1305/4885HTR2A 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.