Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879845 | 0.92 | ITGB3 (0.46) | MEN1KMT2AGRIN2BHDAC3HDAC4 | |
| SCHEMBL5879789 | 0.83 | ITGB3 (0.44) | MEN1KMT2AF2PRSS1NPSR1 | |
| SCHEMBL5879601 | 0.82 | HSD17B10 (0.45) | HRH3KDM4EITGB3ITGAV | |
| SCHEMBL5879645 | 0.74 | ITGB3 (0.61) | POLBKDM4EITGB3ITGAVTSHR | |
| SCHEMBL5879778 | 0.74 | ITGB3 (0.43) | KMT2AKDM4EITGB3ITGAV | |
| SCHEMBL5879698 | 0.71 | ITGB3 (0.71) | ITGB3ITGAVTSHR | |
| SCHEMBL5879664 | 0.71 | ITGB3 (0.52) | MEN1KMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL5879625 | 0.69 | ITGB3 (0.61) | KDM4EITGB3ITGAVTSHR | |
| SCHEMBL5879838 | 0.67 | ITGB3 (0.49) | ITGB3ITGAV | |
| SCHEMBL5879692 | 0.67 | NOS2 (0.48) | MEN1KMT2AKDM4EITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |