Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 2/20 | 0.38 |
| ▸ | SKP1 | P63208 | 2/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879778 | 0.92 | ITGB3 (0.43) | HSD17B10L3MBTL1KDM4EALDH1A1CKS1B | |
| SCHEMBL5879731 | 0.85 | HSD17B10 (0.64) | HSD17B10L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL5879563 | 0.82 | POLB (0.45) | KDM4EITGB3ITGAVHRH3 | |
| SCHEMBL5879673 | 0.80 | HSD17B10 (0.63) | HSD17B10L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL5879664 | 0.79 | ITGB3 (0.52) | KDM4EALDH1A1TP53ITGB3ITGAV | |
| SCHEMBL5879845 | 0.74 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL5879692 | 0.72 | NOS2 (0.48) | HSD17B10L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL5879510 | 0.69 | GRIN2B (0.41) | ITGB3ITGAV | |
| SCHEMBL22776419 | 0.68 | ALDH1A1 (0.52) | HSD17B10KDM4EALDH1A1HPGDCKS1B | |
| SCHEMBL5879540 | 0.67 | ITGB3 (0.63) | ALDH1A1ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105508-B1 | Integrin receptors antagonists | ABBOTT GMBH & CO. KG (DE) | 2006-09-12 | — | — | US | disclosed |