Pyrophosphoric Acid

Pyrophosphoric Acid

SCHEMBL5884527

O=P([O-])([O-])OP(=O)([O-])[O-].[Ca+2].[Mg+2]

nearest known ligand 0.33

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Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.33
CA4 P22748 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
LMNA P02545 1/20 0.33
SLC34A1 Q06495 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrophosphoric Acid SCHEMBL9491044 0.96 CA1 (0.32) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL9490971 0.96 CA1 (0.32) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL59778 0.96 LMNA (0.35) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL18670526 0.96 LMNA (0.35) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL5550827 0.96 LMNA (0.35) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL184653 0.96 LMNA (0.35) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL4418857 0.96 LMNA (0.35) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL75497 0.96 LMNA (0.35) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL9490576 0.93 CA1 (0.30) CA1CA4CA5ACA5BLMNA
Pyrophosphoric Acid SCHEMBL11779407 0.92 CA1 (0.33) CA1CA4CA5ACA5BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116081693-A Method for refining manganese sulfate product by removing impurities from calcium and magnesium 何长荣 2023-05-09 CN claimed
US-7037867-B2 Artificial bone graft substitute using calcium phosphate compounds and method of manufacturing the same SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2006-05-02 US claimed
US-20030193106-A1 Artificial bone graft substitute using calcium phosphate compounds and method of manufacturing the same SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2003-10-16 US claimed
EP-0333053-B1 PHOSPHATE-COATED ELECTROLUMINESCENT PHOSPHOR FOR ELECTROLUMINESCENT LAMP AND A PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-03 EP claimed
CN-116081693-B Method for refining manganese sulfate product by removing impurities from calcium and magnesium 何长荣 2024-11-22 CN disclosed
CN-116768175-A Preparation method and application of amorphous calcium magnesium phosphate with high stability and bioactivity 常州市第二人民医院 2023-09-19 CN disclosed
CN-116081693-A Method for refining manganese sulfate product by removing impurities from calcium and magnesium 何长荣 2023-05-09 CN disclosed
CN-112544609-A Cervical cell sample preservation solution and application thereof 广州市金圻睿生物科技有限责任公司 2021-03-26 CN disclosed
CN-105994252-A Liquid-based thin cell preservation liquid and preparation method thereof 杭州海世嘉生物科技有限公司 2016-10-12 CN disclosed
CN-100378162-C Resin composition for sliding member and sliding member OILES INDUSTRY CO LTD (JP) 2008-04-02 CN disclosed
CN-1823132-A Resin composition for sliding member and sliding member OILES INDUSTRY CO LTD (JP) 2006-08-23 CN disclosed
US-7037867-B2 Artificial bone graft substitute using calcium phosphate compounds and method of manufacturing the same SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2006-05-02 US disclosed
US-20030193106-A1 Artificial bone graft substitute using calcium phosphate compounds and method of manufacturing the same SEOUL NATIONAL UNIVERSITY INDUSTRY FOUNDATION (KR) 2003-10-16 US disclosed
EP-0333053-B1 PHOSPHATE-COATED ELECTROLUMINESCENT PHOSPHOR FOR ELECTROLUMINESCENT LAMP AND A PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-03-03 EP disclosed
EP-0333053-A2 Phosphate-coated electroluminescent phosphor for electroluminescent lamp and a process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-09-20 EP disclosed