Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL5550827 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL4418857 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL18670526 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL59778 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11646886 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL5884527 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL7106242 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11779407 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL9422113 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL452253 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 732 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119943952-A | Positive electrode material, positive electrode plate, battery cell, sodium ion battery and electricity utilization device | 宁德时代新能源科技股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| US-12193868-B2 | Breast calcification imaging phantoms and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2025-01-14 | — | — | US | claimed |
| EP-2934694-B1 | ANTI-PLAQUE ORAL COMPOSITIONS | BHUSHAN RAJIV (US) | 2023-06-28 | — | — | EP | claimed |
| US-20220401057-A1 | Breast Calcification Imaging Phantoms and Methods of Use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2022-12-22 | — | — | US | claimed |
| US-10702463-B2 | Oral compositions for anticavity and desensitization use | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-07-07 | — | — | US | claimed |
| EP-2432444-B1 | ORAL COMPOSITIONS CONTAINING POLYGUANIDINIUM COMPOUNDS AND METHODS OF MANUFACTURE AND USE THEREOF | COLGATE PALMOLIVE CO (US) | 2017-08-23 | — | — | EP | claimed |
| US-20160279042-A1 | Dental Anti-Hypersensitivity Composition and Method | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2016-09-29 | — | — | US | claimed |
| US-20150335557-A1 | ANTI-PLAQUE ORAL COMPOSITIONS | BHUSNAN RAJIV (US) | 2015-11-26 | — | — | US | claimed |
| EP-2934694-A1 | ANTI-PLAQUE ORAL COMPOSITIONS | Bhushan, Rajiv (US) | 2015-10-28 | — | — | EP | claimed |
| WO-2014100775-A1 | ANTI-PLAQUE ORAL COMPOSITIONS | BHUSHAN RAJIV (US) | 2014-06-26 | — | — | WO | claimed |
| US-6524558-B2 | For calcifying dental tissue, e.g., preventing or treating dental hypersensitivity | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK | 2003-02-25 | — | — | US | claimed |
| US-20030017209-A1 | Breath protection microcapsules | WARNER-LAMBERT COMPANY | 2003-01-23 | — | — | US | claimed |
| US-6436370-B1 | ORAL COMPOSITION OF ARGININE BICARBONATE AND CALCIUM CARBONATE PROMOTES THE FORMATION OF DENTINAL TUBULE PLUGS AIDED BY COMBINING CALCIUM AND PHOSPHATE IN THE FLUID | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-08-20 | — | — | US | claimed |
| US-20020068039-A1 | Oral care compositions containing grapefruit seed extract | PAN PAULINE C (US) | 2002-06-06 | — | — | US | claimed |
| US-20020064504-A1 | Dental anti-hypersensitivity composition and method | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2002-05-30 | — | — | US | claimed |
| US-6375459-B1 | Apparatus and method for cleaning teeth | DEKA PRODUCTS LIMITED PARTNERSHIP | 2002-04-23 | — | — | US | claimed |
| EP-1187593-A1 | DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD | The Research Foundation of State University of New York (US) | 2002-03-20 | — | — | EP | claimed |
| WO-2002011641-A2 | APPARATUS AND METHOD FOR CLEANING TEETH | DEKA PRODUCTS LIMITED PARTNERSHIP (US) | 2002-02-14 | — | — | WO | claimed |
| WO-2000078270-A1 | DENTAL ANTI-HYPERSENSITIVITY COMPOSITION AND METHOD | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2000-12-28 | — | — | WO | claimed |
| US-3985675-A | PARTIALLY DEHYDRATED AMORPHOUS CALCIUM SODIUM PYROPHOSPHATE | MONSANTO COMPANY (US) | 1976-10-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030017209-A1 | Breath protection microcapsules | MLYCD, SCD5, FBP1 | LMNA 3674/4885CA1 3185/4885CA4 1720/4885 |
| US-20150335557-A1 | ANTI-PLAQUE ORAL COMPOSITIONS | MGMT, CAPG, TRPM7 | LMNA 3929/4885CA1 2685/4885CA4 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.