Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pyrophosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrophosphoric Acid SCHEMBL184653 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL5550827 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL4418857 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL18670526 | 1.00 | LMNA (0.35) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11646886 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL5884527 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL7106242 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL11779407 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL9422113 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B | |
| Pyrophosphoric Acid SCHEMBL452253 | 0.96 | CA1 (0.33) | LMNACA1CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 24141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4748366-A1 | ORAL CARE COMPOSITION | Haleon UK IP Limited (GB) | 2026-05-27 | — | — | EP | claimed |
| CN-118593383-B | Thickening composition of toothpaste, preparation method and application thereof | Guangzhou Xingxing Yuedong Co.,Ltd. (CN) | 2026-05-26 | — | — | CN | claimed |
| EP-4743599-A1 | METHOD FOR PURIFYING A FILTRATE FROM LEACHING OF BLACK MASS FROM SPENT LITHIUM-ION BATTERIES | Eramet (FR) | 2026-05-20 | — | — | EP | claimed |
| CN-122070120-A | Oral care compositions | 巴斯夫欧洲公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122070150-A | Composition containing BMP-2, and preparation method and application thereof | 杭州九源基因生物医药股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122031281-A | Anhydrous whitening toothpaste | 广州华视光学科技有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122031300-A | Plant cellulose abrasive, preparation method and application thereof, and toothpaste and dentifrice prepared from plant cellulose abrasive | 广州纳英化工有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122012156-A | Lubricating grease applied to automobile transmission device and preparation method thereof | 杭州得润宝科技股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260124126-A1 | BIOACTIVE GLASS CONTAINING DENTIFRICE FORMULATIONS | CORNING INC (US) | 2026-05-07 | — | — | US | claimed |
| EP-4734772-A1 | EXTRUSION-ENCAPSULATED CALCIUM SALTS AS OPACIFYING/WHITENING AGENTS | Capol Inc. (CA) | 2026-05-06 | — | — | EP | claimed |
| US-4043990-A | Process for the recovery of whey protein having improved solution clarity using polyphosphates | STAUFFER CHEMICAL COMPANY (US) | 1977-08-23 | — | — | US | claimed |
| US-RE29182-E | POLYPHOSPHONIC ACIDS | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-12 | — | — | US | claimed |
| US-3989814-A | Calcium pyrophosphate abrasive system for dentifrice | COLGATE-PALMOLIVE COMPANY (US) | 1976-11-02 | — | — | US | claimed |
| US-3985870-A | D-GLUCOHEPTONO-1,4-LACTONE AND CALCIUM COMPOUND ABRASIVE | PFANSTIEHL LABORATORIES, INC. (US) | 1976-10-12 | — | — | US | claimed |
| US-3963832-A | A POLYSACCHARIDE, HUMECTANT, ABRASIVES | TEIJIN LIMITED (JA) | 1976-06-15 | — | — | US | claimed |
| US-3960901-A | Preparation of citraconic acid | PFIZER INC. (US) | 1976-06-01 | — | — | US | claimed |
| US-3959458-A | PHOSPHONATE OR AMINO-PHOSPHORUS COMPOUND | THE PROCTER & GAMBLE COMPANY (US) | 1976-05-25 | — | — | US | claimed |
| US-3957897-A | CATALYZED BY A CALCIUM, MAGNESIUM OR STRONTIUM PYROPHOSPHATE | THE DOW CHEMICAL COMPANY (US) | 1976-05-18 | — | — | US | claimed |
| US-3939100-A | Combination alkali metal pyrophosphate-alkaline earth metal pyrophosphate detergent builder | THE PROCTER & GAMBLE COMPANY (US) | 1976-02-17 | — | — | US | claimed |
| US-3935307-A | POLYSACCHARIDE | TEIJIN LIMITED (JA) | 1976-01-27 | — | — | US | claimed |