Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5887404 | 0.75 | L3MBTL1 (0.40) | MEN1KMT2AL3MBTL1PGR | |
| SCHEMBL5887672 | 0.74 | ESR2 (0.40) | SMN1; SMN2PGR | |
| SCHEMBL1047349 | 0.73 | MEN1 (0.45) | PTGS1MEN1KMT2ANPC1NFKB1 | |
| SCHEMBL17550730 | 0.71 | MEN1 (0.44) | PTGS1MEN1KMT2ANPC1NFKB1 | |
| SCHEMBL10091240 | 0.71 | MEN1 (0.44) | PTGS1MEN1KMT2ANPC1NFKB1 | |
| SCHEMBL5887443 | 0.70 | ACHE (0.46) | MEN1KMT2ANPC1RAB9ARELA | |
| SCHEMBL6047653 | 0.69 | HSD11B1 (0.37) | DHODH | |
| SCHEMBL5887582 | 0.68 | TSHR (0.43) | MEN1KMT2ANPC1RAB9APGR | |
| SCHEMBL22048103 | 0.67 | MEN1 (0.44) | PTGS1MEN1KMT2ANPC1NFKB1 | |
| SCHEMBL10091222 | 0.67 | MEN1 (0.42) | PTGS1MEN1KMT2ANPC1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006501194-A | — | — | 2006-01-12 | — | — | JP | claimed |
| EP-1525190-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004007463-A1 | CCK-1 RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA, N.V. (BE) | 2004-01-22 | — | — | WO | claimed |