Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6914199 | 0.84 | ALDH1A1 (0.32) | MAPT | |
| SCHEMBL7926687 | 0.84 | CYP2A6 (0.30) | — | |
| SCHEMBL7933119 | 0.83 | ALOX5 (0.33) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL5890213 | 0.82 | NPC1 (0.35) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL7936604 | 0.81 | SLC6A4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7935519 | 0.81 | NPC1 (0.32) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL7933124 | 0.81 | ALOX5 (0.34) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL16393655 | 0.80 | HTR1A (0.32) | — | |
| SCHEMBL817965 | 0.79 | NPC1 (0.33) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5859260 | 0.77 | MAPT (0.36) | NPC1MAPTRAB9ASMN1; SMN2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |