Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 4/20 | 0.63 |
| ▸ | MMP2 | P08253 | 4/20 | 0.63 |
| ▸ | MMP13 | P45452 | 3/20 | 0.63 |
| ▸ | MMP9 | P14780 | 3/20 | 0.63 |
| ▸ | MMP3 | P08254 | 2/20 | 0.63 |
| ▸ | MMP7 | P09237 | 2/20 | 0.63 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.54 |
| ▸ | MMP14 | P50281 | 3/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899544 | 0.89 | KAT6A (0.58) | MMP1MMP2MMP13MMP9MMP3 | |
| SCHEMBL23014361 | 0.84 | KAT6A (0.58) | MMP1MMP2MMP13MMP9MMP3 | |
| SCHEMBL5320466 | 0.84 | ALDH1A1 (0.60) | MMP1KAT6AMEN1KMT2AMMP12 | |
| SCHEMBL5899482 | 0.84 | L3MBTL1 (0.60) | MMP1MMP2MMP13MMP9MMP3 | |
| SCHEMBL5899477 | 0.83 | KAT6A (0.65) | MMP1MMP2MMP13MMP9MMP3 | |
| SCHEMBL5899447 | 0.82 | MMP2 (0.70) | MMP1MMP2MMP13MMP9KAT6A | |
| SCHEMBL5899481 | 0.81 | ALDH1A1 (0.56) | MMP1KAT6AMEN1KMT2AMMP12 | |
| SCHEMBL5899467 | 0.79 | KAT6A (0.72) | MMP1MMP2MMP13MMP9MMP3 | |
| SCHEMBL28642342 | 0.78 | MMP1 (0.52) | MMP1MMP2MMP13MMP9MMP3 | |
| SCHEMBL28642340 | 0.78 | MMP1 (0.52) | MMP1MMP2MMP13MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | MMP1 369/4885MMP2 1212/4885MMP13 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.