Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MC3R | P41968 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADA | P00813 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106667 | 0.92 | KCNA5 (0.31) | — | |
| SCHEMBL7650152 | 0.77 | MLYCD (0.42) | — | |
| SCHEMBL7109261 | 0.76 | MLYCD (0.31) | — | |
| SCHEMBL7107198 | 0.76 | — | — | |
| SCHEMBL7106490 | 0.76 | MEN1 (0.36) | KMT2A | |
| SCHEMBL588733 | 0.73 | SIRT6 (0.47) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL7656251 | 0.72 | KDM4E (0.39) | TSHRSCN9AKMT2A | |
| SCHEMBL18230701 | 0.72 | SIRT6 (0.42) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL2518992 | 0.72 | SIRT6 (0.42) | SIRT6ADORA3TSHRMC4RADRA1A | |
| SCHEMBL28330006 | 0.71 | SIRT6 (0.39) | SIRT6ADORA3TSHRMC4RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4185194-A1 | SYSTEMS AND METHODS FOR HOME TRANSDERMAL ASSESSMENT OF GASTROINTESTINAL FUNCTION | MediBeacon Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| EP-4157072-A1 | SENSOR ASSEMBLY WITH MOVABLE SKIN SENSOR | MediBeacon Inc. (US) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021242700-A1 | SENSOR ASSEMBLY WITH MOVABLE SKIN SENSOR | MEDIBEACON INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| EP-3911217-A1 | TWO PIECE SENSOR ASSEMBLY AND METHOD OF USE | MediBeacon Inc. (US) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020149885-A1 | TWO PIECE SENSOR ASSEMBLY AND METHOD OF USE | MEDIBEACON INC. (US) | 2020-07-23 | — | — | WO | disclosed |
| CN-110494167-A | Composition and system for renal function measurement | MEDIBEACON INC | 2019-11-22 | — | — | CN | disclosed |
| US-20140286874-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON, INC. | 2014-09-25 | — | — | US | disclosed |
| EP-2029554-B1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MEDIBEACON LLC (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20120100078-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MALLINCKRODT LLC (US) | 2012-04-26 | — | — | US | disclosed |
| US-8115000-B2 | Pyrazine derivatives and uses thereof in renal monitoring | MALLINCKRODT LLC (US) | 2012-02-14 | — | — | US | disclosed |
| EP-2376459-A1 | MODIFIED PYRAZINE DERIVATIVES AND USES THEREOF | Mallinckrodt LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| US-20110250139-A1 | Modified Pyrazine Derivatives and Uses Thereof | MEDIBEACON, INC. | 2011-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140286874-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | CYP3A5, GLS, XDH | SIRT6 1607/4885ADORA3 638/4885TSHR 1940/4885 |
| US-20110250139-A1 | Modified Pyrazine Derivatives and Uses Thereof | GLS, GLS2, PLPBP | SIRT6 2338/4885ADORA3 3339/4885TSHR 1031/4885 |
| US-20120100078-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | CYP3A5, GLS, XDH | SIRT6 1607/4885ADORA3 638/4885TSHR 1940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.