Water

Water

SCHEMBL5933985

O.O.O.O.O.O.[Mg+2].[O-][Cl+2]([O-])[O-].[O-][Cl+2]([O-])[O-]

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL6547295 0.91 ALDH1A1 (0.67) ALDH1A1
SCHEMBL29433639 0.91
SCHEMBL209413 0.91
Water SCHEMBL4891505 0.83 ALDH1A1 (0.57) ALDH1A1
Water SCHEMBL1412394 0.83 ALDH1A1 (0.57) ALDH1A1
Water SCHEMBL896986 0.83 ALDH1A1 (0.57) ALDH1A1
Water SCHEMBL11409956 0.83 ALDH1A1 (0.57) ALDH1A1
Water SCHEMBL10747924 0.83 ALDH1A1 (0.57) ALDH1A1
Water SCHEMBL72648 0.83 ALDH1A1 (0.57) ALDH1A1
Water SCHEMBL4457293 0.83 ALDH1A1 (0.57) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4071605-A Process for the production of dibasic magnesium hypochlorite OLIN CORPORATION (US) 1978-01-31 US claimed
US-12275853-B2 Process for preparing surface-reacted calcium carbonate OMYA INTERNATIONAL AG (CH) 2025-04-15 US disclosed
EP-3956402-B1 PROCESS FOR PREPARING SURFACE-REACTED CALCIUM CARBONATE OMYA INT AG (CH) 2024-05-01 EP disclosed
CN-117120524-A PVDF film with ultrahigh modulus and response 元平台技术有限公司 2023-11-24 CN disclosed
WO-2023126621-A1 METHOD OF CONTROLLING WEEDS UPL Corporation Limited (MU) 2023-07-06 WO disclosed
WO-2023094952-A1 STABLE AGROCHEMICAL COMPOSITION, PROCESS AND METHOD OF USE THEREOF UPL LIMITED (IN) 2023-06-01 WO disclosed
US-20220243023-A1 CHEMICAL FOAMING OF PVC WITH SURFACE-REACTED CALCIUM CARBONATE (MCC) AND/OR HYDROMAGNESITE OMYA INTERNATIONAL AG (CH) 2022-08-04 US disclosed
US-11363819-B2 Combinations of defoliants UPL LTD (IN) 2022-06-21 US disclosed
US-20220169861-A1 PROCESS FOR PREPARING SURFACE-REACTED CALCIUM CARBONATE OMYA INTERNATIONAL AG (CH) 2022-06-02 US disclosed
EP-3983476-A1 CHEMICAL FOAMING OF PVC WITH SURFACE-REACTED CALCIUM CARBONATE (MCC) AND/OR HYDROMAGNESITE Omya International AG (CH) 2022-04-20 EP disclosed
WO-2020249779-A1 CHEMICAL FOAMING OF PVC WITH SURFACE-REACTED CALCIUM CARBONATE (MCC) AND/OR HYDROMAGNESITE OMYA INTERNATIONAL AG (CH) 2020-12-17 WO disclosed
EP-3750950-A1 CHEMICAL FOAMING OF PVC WITH SURFACE-REACTED CALCIUM CARBONATE (MCC) AND/OR HYDROMAGNESITE Omya International AG (CH) 2020-12-16 EP disclosed
WO-2020212204-A1 PROCESS FOR PREPARING SURFACE-REACTED CALCIUM CARBONATE OMYA INTERNATIONAL AG (CH) 2020-10-22 WO disclosed
EP-3725851-A1 PROCESS FOR PREPARING SURFACE-REACTED CALCIUM CARBONATE Omya International AG (CH) 2020-10-21 EP disclosed
CN-111726989-A Novel combination of defoliants UPL有限公司 2020-09-29 CN disclosed
US-20200296969-A1 NOVEL COMBINATIONS OF DEFOLIANTS UPL LTD (IN) 2020-09-24 US disclosed
EP-3709811-A1 NOVEL COMBINATIONS OF DEFOLIANTS UPL Ltd (IN) 2020-09-23 EP disclosed
WO-2018146566-A1 A LIQUID COMPOSITION AND PROCESS THEREOF UPL LTD (IN) 2018-08-16 WO disclosed
US-20060276339-A1 Methods and compositions for increasing the efficacy of biologically-active ingredients BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2006-12-07 US disclosed
US-4188227-A Method of preparing multi-component chemical compositions BAUER RANDY L 1980-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276339-A1 Methods and compositions for increasing the efficacy of biologically-active ingredients ENPP1, ENPP3, SMPD1 ALDH1A1 2504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.