Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 8/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5174431 | 0.89 | MET (0.47) | METLTA4HMEN1ALDH1A1LMNA | |
| SCHEMBL5175324 | 0.88 | KCNA5 (0.54) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL5175935 | 0.84 | ALDH1A1 (0.51) | EPHX2LTA4HKDM4EMEN1ALDH1A1 | |
| SCHEMBL5174629 | 0.83 | MEN1 (0.57) | EPHX2MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL5174595 | 0.82 | KCNA5 (0.60) | MEN1ALDH1A1LMNAKMT2AKCNA5 | |
| SCHEMBL5175362 | 0.82 | MEN1 (0.55) | LTA4HMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL2476844 | 0.78 | NR1H4 (0.61) | LTA4HMEN1LMNAKMT2ANPC1 | |
| SCHEMBL5175575 | 0.78 | SIGMAR1 (0.53) | HTTEPHX2KDM4EALDH1A1RAB9A | |
| SCHEMBL5174529 | 0.77 | SIGMAR1 (0.63) | KDM4EMEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL5174590 | 0.75 | OPRM1 (0.58) | KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223792-A1 | Phenyl and pyridyl LTA4H modulators | LTA4H, LTB4R, LTC4S | HTT 3249/4885MET 4327/4885EPHX2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.