Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5954538 | 0.79 | CHKA (0.38) | HTR7HTR1BKDM4E | |
| SCHEMBL5953991 | 0.77 | CYP2D6 (0.39) | KDM4E | |
| SCHEMBL5954410 | 0.77 | CCR4 (0.43) | KDM4E | |
| SCHEMBL5954423 | 0.73 | ALDH1A1 (0.46) | KDM4E | |
| SCHEMBL5953966 | 0.72 | ACHE (0.42) | — | |
| SCHEMBL5118491 | 0.70 | ALDH1A1 (0.37) | HTR7KDM4E | |
| SCHEMBL5954527 | 0.68 | IKBKB (0.46) | — | |
| SCHEMBL12251441 | 0.68 | L3MBTL1 (0.41) | KDM4E | |
| SCHEMBL5111007 | 0.68 | HTR7 (0.43) | HTR7KDM4E | |
| SCHEMBL5954407 | 0.68 | ACHE (0.46) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235017-A1 | Cytokine Inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235017-A1 | Cytokine Inhibitors | IL1B, IL1A, IL1R1 | HTR7 2704/4885PIM1 1665/4885PIM2 3121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.