Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5118461 | 0.82 | TBXAS1 (0.46) | ALDH1A1TBXAS1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL5954597 | 0.73 | HTR7 (0.35) | KDM4E | |
| SCHEMBL5954538 | 0.70 | CHKA (0.38) | TSHRKDM4EMEN1KMT2A | |
| SCHEMBL8685340 | 0.69 | LMNA (0.67) | ALDH1A1ALOX15MAPK1HSD17B10TSHR | |
| SCHEMBL5953966 | 0.68 | ACHE (0.42) | ALDH1A1 | |
| SCHEMBL5953991 | 0.67 | CYP2D6 (0.39) | TSHRKDM4ELMNAHPGDSMN1; SMN2 | |
| SCHEMBL28731675 | 0.67 | TBXAS1 (0.57) | ALDH1A1ALOX15MAPK1HSD17B10TSHR | |
| SCHEMBL7590379 | 0.64 | ALDH1A1 (0.60) | ALDH1A1MAPK1TBXAS1KDM4EHTT | |
| SCHEMBL5954527 | 0.64 | IKBKB (0.46) | — | |
| SCHEMBL12251441 | 0.63 | L3MBTL1 (0.41) | ALDH1A1KDM4ELMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060235017-A1 | Cytokine Inhibitors | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-10-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235017-A1 | Cytokine Inhibitors | IL1B, IL1A, IL1R1 | ALDH1A1 1355/4885ALOX15 454/4885MAPK1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.