SCHEMBL5956974

SCHEMBL5956974

Brc1ccc(N(c2cccc3ccccc23)c2cccc3ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.43
ALDH1A1 P00352 5/20 0.36
KMT2A Q03164 1/20 0.36
CYP2A6 P11509 4/20 0.36
TSHR P16473 2/20 0.36
HSD17B10 Q99714 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
KEAP1 Q14145 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30636158 1.00 SIGMAR1 (0.43) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL1456296 0.96 SIGMAR1 (0.43) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL17807014 0.95 ALDH1A1 (0.42) SIGMAR1ALDH1A1KMT2ACYP1A2
SCHEMBL1032732 0.93 SIGMAR1 (0.44) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL29982826 0.93 SIGMAR1 (0.44) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL12156929 0.91 ALDH1A1 (0.42) SIGMAR1ALDH1A1KMT2ACYP1A2
SCHEMBL15768410 0.90 ALDH1A1 (0.44) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL5423604 0.90 SIGMAR1 (0.50) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL5957030 0.89 ALDH1A1 (0.36) SIGMAR1ALDH1A1KMT2ACYP2A6TSHR
SCHEMBL18921875 0.88 ALDH1A1 (0.44) SIGMAR1ALDH1A1CYP1A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112125872-B Heterocyclic compound and organic light-emitting device using same LT素材株式会社 2023-11-10 CN disclosed
US-11812623-B2 Hetero-cyclic compound and organic light emitting device using the same LT MATERIALS CO., LTD. (KR) 2023-11-07 US disclosed
US-11812623-B2 Hetero-cyclic compound and organic light emitting device using the same LT MATERIALS CO., LTD. (KR) 2023-11-07 US disclosed
US-11812623-B2 Hetero-cyclic compound and organic light emitting device using the same LT MATERIALS CO., LTD. (KR) 2023-11-07 US disclosed
US-11271175-B2 Organic electronic element comprising compound for organic electronic element, and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2022-03-08 US disclosed
CN-107531712-B Compound and organic electronic device comprising the same 株式会社LG化学 2021-02-26 CN disclosed
EP-3757095-A2 HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LT Materials Co., Ltd. (KR) 2020-12-30 EP disclosed
CN-112125872-A Heterocyclic compound and organic light-emitting device using the same LT素材株式会社 2020-12-25 CN disclosed
US-20200403157-A1 HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME LT MATERIALS CO., LTD. (KR) 2020-12-24 US disclosed
US-20200235314-A1 ORGANIC ELECTRONIC ELEMENT COMPRISING COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-07-23 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-22 US disclosed
WO-2012091471-A2 COMPOUND AND ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING THE ORGANIC ELECTRONIC ELEMENT 덕산하이메탈(주) (KR) 2012-07-05 WO disclosed
US-8039126-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2011-10-18 US disclosed
US-8039126-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2011-10-18 US disclosed
US-20090058289-A1 Materials for Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2009-03-05 US disclosed
US-20090058289-A1 Materials for Organic Electroluminescent Devices MERCK PATENT GMBH (DE) 2009-03-05 US disclosed
WO-2007115610-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2007-10-18 WO disclosed
US-20060061265-A1 Aromatic amine derivative and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2006-03-23 US disclosed
EP-1559706-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-08-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090058289-A1 Materials for Organic Electroluminescent Devices PNMT, TES, TERT SIGMAR1 1243/4885ALDH1A1 834/4885KMT2A 738/4885
US-11812623-B2 Hetero-cyclic compound and organic light emitting device using the same CRY1, CRY2, PER2 SIGMAR1 3014/4885ALDH1A1 1915/4885KMT2A 1479/4885
US-20200403157-A1 HETERO-CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING THE SAME CRY1, CRY2, PER2 SIGMAR1 3014/4885ALDH1A1 1915/4885KMT2A 1479/4885
US-20060061265-A1 Aromatic amine derivative and organic electroluminescent element employing the same LUC7L2, ARL1, ASH2L SIGMAR1 1876/4885ALDH1A1 770/4885KMT2A 727/4885
US-20120292576-A1 COMPOUNDS FOR ELECTRONIC DEVICES SLCO4C1, SLCO1A2, SLCO2A1 SIGMAR1 2795/4885ALDH1A1 588/4885KMT2A 2324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.