Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.63 |
| ▸ | FBP1 | P09467 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.63 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.63 |
| ▸ | DRD1 | P21728 | 1/20 | 0.63 |
| ▸ | MC5R | P33032 | 1/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | DRD3 | P35462 | 1/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.63 |
| ▸ | CCR2 | P41597 | 1/20 | 0.63 |
| ▸ | HTR6 | P50406 | 1/20 | 0.63 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.63 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351098 | 0.84 | ALDH1A1 (0.72) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL5466260 | 0.83 | ALDH1A1 (0.66) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL14330846 | 0.83 | FBP1 (0.58) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL10448504 | 0.83 | FBP1 (0.58) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL29278086 | 0.82 | ALDH1A1 (0.54) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL31333060 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL22195409 | 0.81 | ALDH1A1 (0.63) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL23894553 | 0.80 | FBP1 (0.55) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL6576658 | 0.80 | PPARA (0.67) | ALDH1A1HSD17B10FBP1HPGDADRA2A | |
| SCHEMBL23894549 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HSD17B10FBP1HPGDADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230383082-A1 | RUBBER FOAM COMPOSITION, FOAM AND MOLDED ARTICLE | DENKA COMPANY LIMITED (JP) | 2023-11-30 | — | — | US | disclosed |
| US-20230383082-A1 | RUBBER FOAM COMPOSITION, FOAM AND MOLDED ARTICLE | DENKA COMPANY LIMITED (JP) | 2023-11-30 | — | — | US | disclosed |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2023-04-27 | — | — | US | disclosed |
| EP-3362100-B1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2022-06-22 | — | — | EP | disclosed |
| US-20210395210-A1 | INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2021-12-23 | — | — | US | disclosed |
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-03-16 | — | — | US | disclosed |
| US-10729738-B2 | Hindered disulfide drug conjugates | GENENTECH, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2019-07-11 | — | — | US | disclosed |
| US-10172821-B2 | Histone deacetylase inhibitors | President & Fellows of Harvard College Dana-Farber Cancer Institute, Inc. (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | ABEL-SANTOS ERNESTO (US) | 2018-01-04 | — | — | US | disclosed |
| US-20090312363-A1 | BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-12-17 | — | — | US | disclosed |
| US-20090209590-A1 | Histone Deacetylase and Tubulin Deacetylase Inhibitors | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2009-08-20 | — | — | US | disclosed |
| US-20080269245-A1 | Dioxanes and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2008-10-30 | — | — | US | disclosed |
| US-7410745-B2 | Photothermographic material and image forming method using same | FUJIFILM CORPORATION (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7244853-B2 | Dioxanes and uses thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-07-17 | — | — | US | disclosed |
| US-20040072849-A1 | Dioxanes and uses thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-04-15 | — | — | US | disclosed |
| EP-0036832-B1 | VULCANIZATION OF RUBBER WITH 2-(ALKYLSULFINYL)-BENZOTHIAZOLES | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1986-06-18 | — | — | EP | disclosed |
| US-4350818-A | CATALYTIC ALKYLATION OF 2-MERCAPTOBENXOTHIAZOLE FOLLOWED BY OXIDATION WITH HYPOCHLORITE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| EP-0036832-A1 | Vulcanization of rubber with 2-(alkylsulfinyl)-benzothiazoles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-09-30 | — | — | EP | disclosed |
| US-4280967-A | Vulcanization of rubber with 2-(alkylsulfinyl)-benzothiazoles | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1981-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210395210-A1 | INHIBITION OF BACTERIAL CHAPERONIN SYSTEMS | HSP90B1, HSP90AB1, HSP90AB2P | ALDH1A1 2932/4885HSD17B10 1242/4885FBP1 2054/4885 |
| US-10945996-B2 | Inhibiting germination of clostridium perfringens spores to reduce necrotic enteritis | CASP3, SI, PYCARD | ALDH1A1 4772/4885HSD17B10 2302/4885FBP1 776/4885 |
| US-20090312363-A1 | BIFUNCTIONAL HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC11, HDAC2 | ALDH1A1 786/4885HSD17B10 410/4885FBP1 1813/4885 |
| US-20090209590-A1 | Histone Deacetylase and Tubulin Deacetylase Inhibitors | HDAC6, HDAC1, HDAC5 | ALDH1A1 320/4885HSD17B10 318/4885FBP1 1567/4885 |
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | ALDH1A1 4604/4885HSD17B10 1813/4885FBP1 2358/4885 |
| US-20040072849-A1 | Dioxanes and uses thereof | UTS2R, HDAC5, AMDHD2 | ALDH1A1 682/4885HSD17B10 892/4885FBP1 78/4885 |
| US-20190209531-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | ALDH1A1 4772/4885HSD17B10 2302/4885FBP1 776/4885 |
| US-10729738-B2 | Hindered disulfide drug conjugates | STS, TST, SCLY | ALDH1A1 143/4885HSD17B10 567/4885FBP1 3728/4885 |
| US-20180000793-A1 | Inhibiting Germination of Clostridium Perfringens Spores to Reduce Necrotic Enteritis | CASP3, SI, PYCARD | ALDH1A1 4772/4885HSD17B10 2302/4885FBP1 776/4885 |
| US-20080269245-A1 | Dioxanes and uses thereof | UTS2R, MAN2B2, AMDHD2 | ALDH1A1 750/4885HSD17B10 877/4885FBP1 128/4885 |
| US-10172821-B2 | Histone deacetylase inhibitors | HDAC1, HDAC11, HDAC7 | ALDH1A1 764/4885HSD17B10 279/4885FBP1 3342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.