SCHEMBL5981763

SCHEMBL5981763

CCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-]

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCAR3 P49019 1/20 0.63
LMNA P02545 2/20 0.60
MAPT P10636 9/20 0.58
KDM4E B2RXH2 1/20 0.58
ALDH1A1 P00352 3/20 0.53
MAPK1 P28482 4/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
CRHBP P24387 1/20 0.52
CRHR2 Q13324 1/20 0.52
POLB P06746 1/20 0.51
PKM P14618 1/20 0.51
GAA P10253 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30169708 1.00 HCAR3 (0.63) HCAR3LMNAMAPTKDM4EALDH1A1
SCHEMBL14063303 0.87 HCAR3 (0.65) HCAR3LMNAMAPTKDM4EALDH1A1
SCHEMBL8107611 0.86 MAPT (0.60) LMNAMAPTKDM4EALDH1A1MAPK1
SCHEMBL14294847 0.84 MAPT (0.69) HCAR3LMNAMAPTKDM4EALDH1A1
SCHEMBL4303213 0.83 MAPT (0.52) LMNAMAPTKDM4EALDH1A1MAPK1
SCHEMBL29306545 0.83 HCAR3 (0.67) HCAR3LMNAMAPTKDM4EALDH1A1
SCHEMBL8147273 0.83 MAPT (0.65) HCAR3LMNAMAPTKDM4EALDH1A1
SCHEMBL6250970 0.83 KAT2B (0.66) HCAR3LMNAMAPTALDH1A1MAPK1
SCHEMBL10893359 0.82 MAPT (0.51) LMNAMAPTKDM4EALDH1A1MAPK1
SCHEMBL10891353 0.82 MAPT (0.59) LMNAMAPTKDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006060654-A2 PESTICIDAL COMPOSITIONS AND METHODS DIVERGENCE, INC. (US) 2006-06-08 WO claimed
US-20050203067-A1 Pesticidal compositions and methods DIVERGENCE, INC. 2005-09-15 US claimed
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2026-03-31 US disclosed
EP-3642175-B1 COMPOSITION FOR SINGLE-BASE PROPELLING POWDER FOR AMMUNITION AND AMMUNITION PROVIDED WITH SUCH COMPOSITION SIMMEL DIFESA SPA (IT) 2024-03-06 EP disclosed
US-20230295095-A1 NOVEL FUSED-HETEROCYCLYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-09-21 US disclosed
EP-4169905-A1 NOVEL FUSED HETEROCYCLIC CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF Korea Institute of Science and Technology (KR) 2023-04-26 EP disclosed
CN-115867277-A Novel fused heterocyclyl-carbohydrazone acyldinitrile compounds and use thereof 韩国科学技术研究院 2023-03-28 CN disclosed
CN-110914224-B Composition for single-base propellant powder for ammunition and ammunition provided with such composition 西梅尔迪菲萨股份有限公司 2023-01-10 CN disclosed
WO-2021256899-A1 NOVEL FUSED HETEROCYCLIC CARBONOHYDRAZONOYL DICYANIDE COMPOUND AND USE THEREOF 한국과학기술연구원 2021-12-23 WO disclosed
US-20210147312-A1 Composition for single-base propelling powder for ammunition and ammunition provided with such composition KNDS AMMO ITALY S.P.A., (IT) 2021-05-20 US disclosed
CN-110914224-A Composition for single-base propellant powder for ammunition and ammunition provided with such composition 西梅尔迪菲萨股份有限公司 2020-03-24 CN disclosed
EP-0282978-B1 Surface acoustic wave convolver with dielectric film of high non-linear effect CANON KK (JP) 1993-12-01 EP disclosed
EP-0284229-B1 NONLINEAR OPTICAL MATERIAL AND METHOD FOR ORIENTATION THEREOF CANON KABUSHIKI KAISHA (JP) 1993-07-21 EP disclosed
US-5037582-A Nonlinear optical material and method for orientation thereof CANON KABUSHIKI KAISHA (JP) 1991-08-06 US disclosed
US-4946261-A Recording method and recording apparatus CANON KABUSHIKI KAISHA (JP) 1990-08-07 US disclosed
US-4882715-A Surface acoustic wave convolver with dielectric film of high non-linear effect CANON KABUSHIKI KAISHA (JP) 1989-11-21 US disclosed
EP-0295145-A2 Recording method and recording apparatus CANON KABUSHIKI KAISHA (JP) 1988-12-14 EP disclosed
EP-0284229-A1 Nonlinear optical material and method for orientation thereof CANON KABUSHIKI KAISHA (JP) 1988-09-28 EP disclosed
EP-0282978-A2 Surface acoustic wave convolver with dielectric film of high non-linear effect CANON KABUSHIKI KAISHA (JP) 1988-09-21 EP disclosed
US-4387247-A Catalytic reduction of nitro aromatic compounds with hydrogen sulfide and carbon monoxide ALLIED CORPORATION (US) 1983-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050203067-A1 Pesticidal compositions and methods ACHE, DDT, PTMS HCAR3 773/4885LMNA 1278/4885MAPT 3378/4885
US-12590066-B2 Fused-heterocyclyl-carbonohydrazonoyl dicyanide compounds and use thereof H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CLIC1 HCAR3 162/4885LMNA 2642/4885MAPT 4672/4885
US-20230295095-A1 NOVEL FUSED-HETEROCYCLYL-CARBONOHYDRAZONOYL DICYANIDE COMPOUNDS AND USE THEREOF CBR3, DBF4, DDT HCAR3 1377/4885LMNA 1471/4885MAPT 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.