Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.34 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416281 | 0.75 | LIMK1 (0.47) | GPR3KDM4EL3MBTL1LOXL2MCL1 | |
| SCHEMBL787663 | 0.75 | HSD11B1 (0.43) | GPR3KDM4EL3MBTL1MCL1RXFP1 | |
| SCHEMBL6369758 | 0.75 | GPR3 (0.41) | GPR3KDM4EL3MBTL1LOXL2MCL1 | |
| SCHEMBL1477083 | 0.72 | CYP1A2 (0.51) | GPR3KDM4EL3MBTL1LOXL2MCL1 | |
| SCHEMBL2165461 | 0.70 | LMNA (0.43) | GPR3KDM4ETSHRALDH1A1LMNA | |
| SCHEMBL6957613 | 0.68 | ACLY (0.44) | GPR3KDM4EL3MBTL1LOXL2MCL1 | |
| SCHEMBL7116533 | 0.68 | MCL1 (0.51) | GPR3KDM4EL3MBTL1LOXL2MCL1 | |
| SCHEMBL7384536 | 0.68 | L3MBTL1 (0.43) | L3MBTL1RXFP1ALDH1A1TDP1 | |
| SCHEMBL10929650 | 0.67 | KDM4E (0.41) | GPR3KDM4EL3MBTL1MCL1ALDH1A1 | |
| SCHEMBL5440971 | 0.67 | GPR3 (0.40) | GPR3KDM4EL3MBTL1LOXL2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694650-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005058842-A1 | 1-N-PHENYL-AMINO-1H-IMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2005-06-30 | — | — | WO | disclosed |