Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.56 |
| ▸ | POLD1 | P28340 | 1/20 | 0.56 |
| ▸ | TK1 | P04183 | 8/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triphosphate SCHEMBL27892350 | 0.88 | POLB (0.61) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL18855348 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL265387 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| Triphosphate SCHEMBL6138574 | 0.87 | POLB (0.58) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL30586988 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL77582 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL3031874 | 0.87 | POLB (0.68) | POLBPOLA1POLD1TK1BCHE | |
| SCHEMBL154177 | 0.87 | POLB (0.65) | POLBPOLA1POLD1TK1BCHE | |
| Triphosphate SCHEMBL6066341 | 0.86 | POLB (0.58) | POLBPOLA1POLD1TK1ALB | |
| SCHEMBL19126902 | 0.85 | POLB (0.56) | POLBPOLA1POLD1TK1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2535423-B1 | Labeling and detection of nucleic acids | LIFE TECHNOLOGIES CORP (US) | 2019-05-15 | — | — | EP | disclosed |
| US-20140336079-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | LIFE TECHNOLOGIES CORP (US) | 2014-11-13 | — | — | US | disclosed |
| EP-2535423-A2 | Labeling and detection of nucleic acids | Life Technologies Corporation (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2224013-B1 | Methods for the determination of telomerase activity using click chemistry | LIFE TECHNOLOGIES CORP (US) | 2012-12-05 | — | — | EP | disclosed |
| US-8114636-B2 | Labeling and detection of nucleic acids | Life Technologies Corporation (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100261181-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | Life Technologies Corporation (US) | 2010-10-14 | — | — | US | disclosed |
| EP-2224013-A1 | Methods for the determination of telomerase activity using click chemistry | Life Technologies Corporation (US) | 2010-09-01 | — | — | EP | disclosed |
| US-20080050731-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | INVITROGEN CORPORATION (US) | 2008-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261181-A1 | LABELING AND DETECTION OF NUCLEIC ACIDS | RNGTT, ADAR, ALKBH1 | POLB 159/4885POLA1 153/4885POLD1 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.