Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5996499 | 0.80 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1LMNAKMT2ARAB9A | |
| SCHEMBL6255018 | 0.75 | GHSR (0.46) | ALDH1A1L3MBTL1LMNAKMT2AMAPT | |
| SCHEMBL6255022 | 0.75 | GHSR (0.46) | ALDH1A1L3MBTL1LMNAKMT2AMAPT | |
| SCHEMBL3392200 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAKMT2AMAPTCA1 | |
| SCHEMBL27713867 | 0.71 | F2 (0.50) | ALDH1A1L3MBTL1LMNAKMT2ARAB9A | |
| SCHEMBL7984352 | 0.71 | BCHE (0.47) | ALDH1A1L3MBTL1KMT2AMMP1MMP2 | |
| SCHEMBL14676357 | 0.70 | CA12 (0.50) | ALDH1A1L3MBTL1LMNAKMT2AMAPT | |
| SCHEMBL7415883 | 0.69 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1LMNAKMT2ARAB9A | |
| SCHEMBL7981503 | 0.69 | EGFR (0.43) | ALDH1A1KMT2AMAPTMMP1MMP2 | |
| SCHEMBL634085 | 0.69 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142586-A1 | Synthesis of 2-alkyl amino acids | CHORGHADE MUKUND S | 2006-06-29 | — | — | US | disclosed |
| US-7038073-B2 | Synthesis of 2-alkyl amino acids | GENZYME CORPORATION (US) | 2006-05-02 | — | — | US | disclosed |
| EP-1529037-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | Genzyme Corporation (US) | 2005-05-11 | — | — | EP | disclosed |
| US-20040006224-A1 | Synthesis of 2-alkyl amino acids | GENZYME CORPORATION | 2004-01-08 | — | — | US | disclosed |
| WO-2003097622-A2 | SYNTHESIS OF 2-ALKYLCYSTEINES, 2-(HYDROXYLATED PHENYL)-4-ALKYLTHIAZOLINE-4-CARBOXYLIC ACIDS AND DERIVATIVES THEREOF | GENZYME CORPORATION (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142586-A1 | Synthesis of 2-alkyl amino acids | ASNS, AAAS, FTH1 | HDAC3 4077/4885HDAC4 3358/4885HDAC1 4230/4885 |
| US-20040006224-A1 | Synthesis of 2-alkyl amino acids | ASNS, AAAS, FTH1 | HDAC3 4077/4885HDAC4 3358/4885HDAC1 4230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.