Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 3/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.46 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395319 | 0.93 | LPL (0.54) | LPLLIPG | |
| SCHEMBL12040880 | 0.93 | LPL (0.54) | LPLLIPG | |
| SCHEMBL10061751 | 0.88 | HTR2C (0.43) | HTR2CHTR6MEN1KMT2A | |
| SCHEMBL15564559 | 0.83 | CYP4F2 (0.46) | LPLLIPGHTR2CHTR6MEN1 | |
| SCHEMBL347126 | 0.81 | LPL (0.57) | LPLLIPGSKP2NPC1HPGD | |
| SCHEMBL674816 | 0.81 | LPL (0.54) | LPLLIPGHTR2CHTR6 | |
| SCHEMBL7469370 | 0.80 | MAPT (0.39) | LPLLIPGHTR2CHTR6MEN1 | |
| SCHEMBL5022962 | 0.79 | SIGMAR1 (0.50) | MEN1KMT2A | |
| SCHEMBL12410556 | 0.79 | HPGD (0.47) | SKP2NPC1HPGDMAPK1HTT | |
| SCHEMBL10610847 | 0.79 | LPL (0.56) | LPLLIPGHTR2CHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230011240-A1 | MODIFIED ARCHAEAL FAMILY B POLYMERASES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-12 | — | — | US | disclosed |
| US-20210009551-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROSIS OR CANCER | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-01-14 | — | — | US | disclosed |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-28 | — | — | US | disclosed |
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | disclosed |
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| CN-101370806-A | Substituted 4-phenylpiperidines | SPEEDEL EXPERIMENTA AG (CH) | 2009-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | LPL 2477/4885LIPG 3249/4885SKP2 2084/4885 |
| US-20210009551-A1 | COMPOUNDS AND METHODS FOR TREATING FIBROSIS OR CANCER | MMP1, MMP8, SERPINB1 | LPL 992/4885LIPG 443/4885SKP2 3184/4885 |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | LPL 2477/4885LIPG 3249/4885SKP2 2084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.