Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.49 |
| ▸ | CCR6 | P51684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30027465 | 1.00 | KDM4E (0.59) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL692544 | 0.79 | KDM4E (0.49) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL571602 | 0.78 | KDM4E (0.63) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL6268556 | 0.78 | KDM4E (0.55) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL691962 | 0.76 | KDM4E (0.54) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL28990432 | 0.76 | PKM (0.55) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL30385711 | 0.76 | PKM (0.55) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL29155525 | 0.76 | KDM4E (0.54) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL571737 | 0.75 | KDM4E (0.56) | KDM4EALOX12TDP1CYP3A4GAA | |
| SCHEMBL168947 | 0.75 | KDM4E (0.62) | KDM4EALOX12TDP1CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120101287-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2012-04-26 | — | — | US | disclosed |
| US-8114991-B2 | Used for the control of a range of harmful weeds | BAYER CROPSCIENCE AG (DE) | 2012-02-14 | — | — | US | disclosed |
| US-20110152082-A1 | LIQUID FORMULATIONS | BAYER CROPSCIENCE AG (DE) | 2011-06-23 | — | — | US | disclosed |
| EP-2305655-A2 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators. | Bayer CropScience AG (DE) | 2011-04-06 | — | — | EP | disclosed |
| US-20070021303-A1 | Safening method | BAYER CROPSCIENCE AG (DE) | 2007-01-25 | — | — | US | disclosed |
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | BAYER CROPSCIENCE GMBH (DE) | 2005-03-31 | — | — | US | disclosed |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | DDT, B2M, MTX2 | KDM4E 4686/4885ALOX12 580/4885TDP1 4498/4885 |
| US-20070021303-A1 | Safening method | BCL2, BCL2L11, CYP51A1 | KDM4E 3362/4885ALOX12 169/4885TDP1 1593/4885 |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | CYP4Z1, IL4I1, BCAT1 | KDM4E 743/4885ALOX12 2707/4885TDP1 2791/4885 |
| US-20120101287-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | IL4I1, DAO, CYP4Z1 | KDM4E 591/4885ALOX12 2916/4885TDP1 2891/4885 |
| US-20110152082-A1 | LIQUID FORMULATIONS | CBX3, CBX6, IPO11 | KDM4E 273/4885ALOX12 3315/4885TDP1 2222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.