Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 1/20 | 0.41 |
| ▸ | RHOA | P61586 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002774 | 0.84 | FAAH (0.46) | FAAHPPARGPPARAPTGESALOX5 | |
| SCHEMBL2088414 | 0.83 | FAAH (0.48) | FAAHPPARGPPARAPTGESALOX5 | |
| SCHEMBL13303326 | 0.83 | LTA4H (0.55) | MAPK1SMN1; SMN2LTA4HNR5A1SLC2A1 | |
| SCHEMBL28983023 | 0.78 | NR5A1 (0.65) | LTA4HNR5A1SLC2A1 | |
| SCHEMBL533759 | 0.78 | NR5A1 (0.65) | LTA4HNR5A1SLC2A1 | |
| SCHEMBL12409185 | 0.76 | CHRNB2 (0.54) | PPARALTA4HNR5A1 | |
| SCHEMBL6002773 | 0.75 | RHOC (0.48) | FAAHRHOCRHOALTA4H | |
| SCHEMBL15000370 | 0.75 | LTA4H (0.47) | FAAHMAPK1SMN1; SMN2LTA4HNR5A1 | |
| SCHEMBL5016258 | 0.75 | FAAH (0.48) | FAAHPPARGALOX5RHOCRHOA | |
| SCHEMBL26035837 | 0.75 | PSEN1 (0.46) | FAAHPPARGPPARAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |