Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045894 | 0.83 | HSD11B1 (0.41) | TRPA1TSHR | |
| SCHEMBL6001640 | 0.76 | METAP2 (0.33) | ALDH1A1 | |
| SCHEMBL4045966 | 0.73 | IDO1 (0.46) | ALDH1A1 | |
| SCHEMBL15935183 | 0.70 | TRPA1 (0.38) | TRPA1ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL3623073 | 0.70 | CA2 (0.43) | TRPA1ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL1194484 | 0.70 | ALDH1A1 (0.55) | TRPA1ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL27584597 | 0.68 | KIF11 (0.42) | ALDH1A1TSHRTDP1KIF11 | |
| SCHEMBL15935177 | 0.68 | TRPA1 (0.39) | TRPA1ALDH1A1TSHRTDP1CA2 | |
| SCHEMBL545684 | 0.68 | ALDH1A1 (0.52) | TRPA1ALDH1A1TSHRTDP1CA2 | |
| Phosphine SCHEMBL2238711 | 0.68 | ALDH1A1 (0.52) | TRPA1ALDH1A1TSHRTDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |