SCHEMBL6004246

SCHEMBL6004246

CC1=CC(=CCc2ccccc2)[C]=C1C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 1/20 0.33
ALDH1A1 P00352 2/20 0.32
OPRK1 P41145 1/20 0.32
TSHR P16473 1/20 0.32
HPGD P15428 1/20 0.32
EPHX2 P34913 2/20 0.32
P2RX7 Q99572 2/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3163737 0.75 ALDH1A1 (0.34) HSD11B1ALDH1A1OPRK1TSHRHPGD
SCHEMBL3149767 0.69 FAAH (0.36) HSD11B1ALDH1A1TSHREPHX2P2RX7
SCHEMBL3159136 0.64 NPC1 (0.33) ALDH1A1TSHRMEN1KMT2A
SCHEMBL677280 0.64 OPRK1 (0.44) HSD11B1ALDH1A1OPRK1TSHRHPGD
SCHEMBL677286 0.62 P2RX7 (0.44) ALDH1A1OPRK1TSHRHPGDEPHX2
SCHEMBL3157635 0.61 HSD11B1 (0.31) HSD11B1TSHR
SCHEMBL28731868 0.59 LMNA (0.53) ALDH1A1OPRK1TSHRHPGDEPHX2
SCHEMBL27599327 0.59 ALDH1A1 (0.53) HSD11B1ALDH1A1OPRK1TSHRHPGD
SCHEMBL181479 0.57 GRIN2D (0.62) HSD11B1ALDH1A1EPHX2MEN1KMT2A
SCHEMBL28731865 0.57 MEN1 (0.43) HSD11B1ALDH1A1OPRK1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060276607-A1 Propylene copolymer, polypropylene composition, and uses thereof, transition metal compounds and catalyst for olefin polymerization MITSUI CHEMICALS, INC. (JP) 2006-12-07 US disclosed