Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 7/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 3/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004082 | 0.84 | CBFB (0.37) | SRCTGFBR1MEN1KMT2AMET | |
| SCHEMBL6004710 | 0.82 | CYP3A4 (0.42) | METKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6004984 | 0.80 | PDE3B (0.39) | SRCTGFBR1METGAAKDM4E | |
| SCHEMBL6004207 | 0.80 | CYP1A2 (0.37) | TGFBR1MEN1KMT2AMETGAA | |
| SCHEMBL6005438 | 0.80 | MET (0.35) | TGFBR1METKDM4EUSP2ALDH1A1 | |
| SCHEMBL6002914 | 0.79 | PDGFRB (0.49) | SRCTGFBR1METKDRMST1R | |
| SCHEMBL6004277 | 0.79 | NPSR1 (0.43) | SRCTGFBR1KMT2AMETKDR | |
| SCHEMBL6004278 | 0.78 | KDR (0.49) | SRCTGFBR1METKDR | |
| SCHEMBL6004800 | 0.78 | KDR (0.40) | MEN1KMT2AMETGAAKDM4E | |
| SCHEMBL6005260 | 0.76 | MET (0.50) | SRCTGFBR1METKDRMST1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |