Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 13/20 | 0.42 |
| ▸ | FPR1 | P21462 | 12/20 | 0.42 |
| ▸ | CALCA | P06881 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015065 | 0.90 | ALDH1A1 (0.43) | FPR2CYP3A4CALCRL | |
| SCHEMBL3451041 | 0.90 | ALDH1A1 (0.43) | FPR2CYP3A4CALCRL | |
| SCHEMBL3448717 | 0.87 | FPR2 (0.52) | FPR2FPR1 | |
| SCHEMBL6015050 | 0.85 | YAP1 (0.45) | YAP1CALCRL | |
| SCHEMBL6015112 | 0.83 | CCR1 (0.38) | FPR2 | |
| SCHEMBL6015116 | 0.83 | CYP51A1 (0.42) | FPR2CALCACALCRL | |
| SCHEMBL6015029 | 0.81 | CCR1 (0.40) | CYP3A4CALCRL | |
| SCHEMBL6015073 | 0.81 | CCR1 (0.40) | — | |
| SCHEMBL6015003 | 0.80 | CCKBR (0.40) | — | |
| SCHEMBL6015148 | 0.79 | UBE2N (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695961-A1 | UREA DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2006-08-30 | — | — | EP | disclosed |