Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 9/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 2/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3787216 | 0.81 | SSTR4 (0.38) | SSTR4CTSC | |
| SCHEMBL969313 | 0.77 | CHRNB2 (0.46) | SSTR4 | |
| SCHEMBL23303999 | 0.76 | CHRNB2 (0.42) | SSTR4 | |
| SCHEMBL3742282 | 0.75 | SSTR4 (0.45) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL8292968 | 0.75 | SSTR4 (0.45) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| Hydrochloric Acid SCHEMBL4031709 | 0.74 | SSTR4 (0.44) | SSTR4SSTR1SSTR2SSTR3SSTR5 | |
| SCHEMBL6937389 | 0.73 | SSTR4 (0.43) | SSTR4 | |
| SCHEMBL5948132 | 0.73 | SSTR4 (0.41) | SSTR4 | |
| SCHEMBL21484361 | 0.73 | SSTR4 (0.41) | SSTR4 | |
| SCHEMBL798154 | 0.70 | SLC6A3 (0.53) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252751-A1 | 3-Aminopyrrolidine derivaties as modulators of chemokine receptors | INCYTE HOLDINGS CORPORATION | 2006-11-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252751-A1 | 3-Aminopyrrolidine derivaties as modulators of chemokine receptors | CCR2, CXCR3, CCR5 | SSTR4 823/4885SSTR1 507/4885SSTR2 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.