Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 6/20 | 0.51 |
| ▸ | HINT1 | P49773 | 3/20 | 0.49 |
| ▸ | KRAS | P01116 | 5/20 | 0.48 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
| ▸ | IMPDH1 | P20839 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Guanosine SCHEMBL7571212 | 1.00 | NT5E (0.55) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL8425223 | 0.93 | NT5E (0.58) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL4816737 | 0.89 | TGM2 (0.55) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL3264840 | 0.89 | TGM2 (0.55) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL8429254 | 0.89 | TGM2 (0.55) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL28068227 | 0.87 | NT5E (0.58) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL28048641 | 0.87 | TGM2 (0.57) | NT5ETGM2HPGDIMPDH2HINT1 | |
| Guanosine SCHEMBL19810340 | 0.85 | HPGD (0.59) | NT5ETGM2HPGDHINT1GSK3A | |
| Guanosine SCHEMBL19810339 | 0.85 | HPGD (0.59) | NT5ETGM2HPGDHINT1GSK3A | |
| Guanosine SCHEMBL3977221 | 0.85 | HPGD (0.59) | NT5ETGM2HPGDHINT1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156431-A1 | L-gulose dependent vitamin C synthesis | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2006-07-13 | — | — | US | disclosed |
| EP-1649034-A1 | L-GULOSE DEPENDENT VITAMIN C SYNTHESIS | VIB vzw (BE) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014844-A1 | L-GULOSE DEPENDENT VITAMIN C SYNTHESIS | VIB VZW (BE) | 2005-02-17 | — | — | WO | disclosed |