Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1044315 | 0.87 | KCNH2 (0.58) | KCNH2POLBSIGMAR1LMNANR1I2 | |
| SCHEMBL797985 | 0.83 | ALDH1A1 (0.59) | KCNH2SIGMAR1LMNANR1I2ADORA3 | |
| SCHEMBL10212101 | 0.83 | HRH3 (0.65) | KCNH2SIGMAR1MEN1KMT2AKDM4E | |
| SCHEMBL12891080 | 0.83 | KCNH2 (0.48) | KCNH2POLBSIGMAR1LMNANR1I2 | |
| SCHEMBL12666600 | 0.82 | HRH3 (0.69) | KCNH2POLBSIGMAR1MEN1KMT2A | |
| SCHEMBL270997 | 0.82 | HRH3 (0.69) | KCNH2POLBSIGMAR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7407307 | 0.80 | HRH3 (0.67) | KCNH2POLBSIGMAR1MEN1KMT2A | |
| SCHEMBL978708 | 0.80 | KCNH2 (0.52) | KCNH2POLBSIGMAR1LMNANR1I2 | |
| SCHEMBL798068 | 0.80 | HRH3 (0.58) | KCNH2POLBSIGMAR1LMNATEAD1 | |
| SCHEMBL270535 | 0.80 | LMNA (0.62) | KCNH2SIGMAR1LMNANR1I2ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7081557-B2 | Method for the oligomerization of olefins using a cycloalkylalkyl-substituted triazacyclohexane | BASELL POLYOLEFINE GMBH (DE) | 2006-07-25 | — | — | US | disclosed |
| EP-1483051-B1 | METHOD FOR THE OLIGOMERIZATION OF OLEFINS USING A CYCLOALKYLALKYL-SUBSTITUTED TRIAZACYCLOHEXANE | BASELL POLYOLEFINE GMBH (DE) | 2005-12-14 | — | — | EP | disclosed |
| US-20050256357-A1 | Method for the oligomerization of olefins using a cycloalkylalkyl-substituted triazacyclohexane | BASELL POLYOLEFINE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256357-A1 | Method for the oligomerization of olefins using a cycloalkylalkyl-substituted triazacyclohexane | ALOX12, ALOX15B, ALOX15 | KCNH2 1640/4885POLB 2187/4885SIGMAR1 1941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.