SCHEMBL6049

SCHEMBL6049

O=C=NCc1ccccc1F

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.43
LMNA P02545 2/20 0.41
IDO1 P14902 2/20 0.41
ALDH1A1 P00352 4/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
POLB P06746 1/20 0.38
KDM4E B2RXH2 1/20 0.38
RECQL P46063 1/20 0.36
AOC3 Q16853 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127043 0.84 GABRA1 (0.41) TAAR1ALDH1A1
SCHEMBL29364508 0.84 GABRA1 (0.41) TAAR1ALDH1A1
SCHEMBL1648245 0.84 RIPK1 (0.39) TAAR1LMNAIDO1ALDH1A1RECQL
Benzene SCHEMBL28107745 0.82 GABRA1 (0.40) ALDH1A1
SCHEMBL28225610 0.82 GABRA1 (0.40) ALDH1A1
Water SCHEMBL5172983 0.82 GABRA1 (0.40) ALDH1A1
SCHEMBL1847577 0.80 TAAR1 (0.50) TAAR1LMNAIDO1ALDH1A1L3MBTL1
SCHEMBL27885870 0.79 GABRA1 (0.35)
SCHEMBL3933178 0.79 MIF (0.52) TAAR1LMNAIDO1ALDH1A1AOC3
SCHEMBL8763269 0.78 GABRA1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
CN-113226356-B Activation of pyruvate kinase R 诺沃挪第克健康护理股份公司 2025-03-04 CN disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 EP disclosed
WO-2024236000-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2024-11-21 WO disclosed
EP-4464727-A1 ESTERIFIED ETHANOLAMINES FOR THE PREPARATION OF ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-11-20 EP disclosed
US-12122778-B2 Activating pyruvate kinase R NOVO NORDISK HEALTH CARE AG (CH) 2024-10-22 US disclosed
EP-3852791-B1 ACTIVATING PYRUVATE KINASE R NOVO NORDISK HEALTHCARE AG (CH) 2024-07-03 EP disclosed
US-20240150515-A1 Low Viscosity Catalyst Compositions for Producing Isocyanurate Polymers COVESTRO DEUTSCHLAND AG (DE) 2024-05-09 US disclosed
EP-4298140-A1 LOW VISCOSITY CATALYST COMPOSITIONS FOR PRODUCING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2024-01-03 EP disclosed
CN-116917364-A Low viscosity catalyst composition for producing isocyanurate polymers 科思创德国股份有限公司 2023-10-20 CN disclosed
WO-2004054579-A1 2-PYRIDYL AND 2-PYRIMIDYL CYCLOALKYLENE AMIDE COMPOUNDS AS NR2B RECEPTOR ANTAGONISTS PFIZER JAPAN INC. (JP) 2004-07-01 WO disclosed
US-20040014688-A1 Oxolide antibacterials ABBVIE INC. 2004-01-22 US disclosed
EP-1088813-B1 Urethane group containing photoinitiators for cationic curing GOLDSCHMIDT AG TH (DE) 2003-12-03 EP disclosed
WO-2003090760-A1 OXOLIDE ANTIBACTERIALS ABBOTT LABORATORIES (US) 2003-11-06 WO disclosed
US-6380277-B1 AS POLYMERIZATION CATALYST, USED FOR THE RADIATION CURING OF CATIONICALLY CURING FORMULATIONS GOLDSCHMIDT AG (DE) 2002-04-30 US disclosed
EP-1088813-A2 Urethane group containing photoinitiators for cationic curing Goldschmidt AG (DE) 2001-04-04 EP disclosed
EP-0752991-B1 IMIDAZO[1,2-a]INDENO[1,2-e]PYRAZIN-4-ONES ANTAGONISTS OF AMPA AND NMDA RECEPTORS RHONE POULENC RORER SA (FR) 1999-05-26 EP disclosed
US-5789406-A Indeno 1,2-E!pyrazine-4-ones, their preparation and the medicaments containing them RHONE-POULENC RORER S.A. (FR) 1998-08-04 US disclosed
EP-0752991-A1 INDENO[1,2-e]PYRAZINE-4-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME Aventis Pharma S.A. (FR) 1997-01-15 EP disclosed
WO-1995026349-A1 INDENO[1,2-e]PYRAZINE-4-ONES, PREPARATION THEREOF AND DRUGS CONTAINING SAME RHONE-POULENC RORER S.A. (FR) 1995-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014688-A1 Oxolide antibacterials OGFOD1, PGLS, OXER1 TAAR1 2998/4885LMNA 2757/4885IDO1 753/4885
US-12122778-B2 Activating pyruvate kinase R PDK1, PDK2, PKLR TAAR1 4374/4885LMNA 2040/4885IDO1 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.