SCHEMBL6053382

SCHEMBL6053382

O=S(=O)(Cl)c1cccc(Oc2ccccc2)c1S(=O)(=O)Cl

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.41
GAA P10253 1/20 0.41
KMT2A Q03164 1/20 0.41
CASP1 P29466 1/20 0.40
DPP4 P27487 1/20 0.40
PTGS2 P35354 1/20 0.40
PGR P06401 4/20 0.39
NR1H2 P55055 1/20 0.39
CTNNB1 P35222 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
RIPK1 Q13546 1/20 0.38
TSHR P16473 1/20 0.38
ACLY P53396 1/20 0.37
SOS1 Q07889 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL997994 0.85 CASP1 (0.48) POLBMAPTLMNAGAAKMT2A
SCHEMBL512464 0.77 CASP1 (0.44) POLBMAPTLMNAGAAKMT2A
SCHEMBL11600047 0.76 CASP1 (0.43) POLBMAPTLMNAGAAKMT2A
SCHEMBL5682816 0.76 CASP1 (0.52) LMNAGAAKMT2ACASP1PTGS2
SCHEMBL677096 0.75 PTGS2 (0.42) POLBMAPTLMNAGAAKMT2A
SCHEMBL305265 0.74 ALDH1A1 (0.42) GAATSHRCA1CA2CA9
SCHEMBL926865 0.74 CA12 (0.49) MAPTLMNACASP1L3MBTL1SOS1
SCHEMBL30307015 0.74 TRPV4 (0.46) MAPTLMNAKMT2APGR
SCHEMBL7386055 0.74 TRPV4 (0.46) MAPTLMNAKMT2APGR
SCHEMBL146565 0.74 CASP1 (0.50) LMNAGAAKMT2ACASP1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1431365-B1 Heat resistant, impact resistant, acrylic/epoxy adhesives ILLINOIS TOOL WORKS (US) 2006-07-19 EP disclosed
EP-1431365-A1 Heat resistant, impact resistant, acrylic/epoxy adhesives ILLINOIS TOOL WORKS INC. (US) 2004-06-23 EP disclosed
EP-0489573-B1 Separation of hydrocarbon dewaxing and deasphalting solvents from dewaxed and/ or deasphalted oil using interfacially polymerized membrane EXXON RESEARCH ENGINEERING CO (US) 1995-09-20 EP disclosed
EP-0485077-B1 Solvent extraction process involving membrane separation of extract phase and/or intermediate zone phase with pseudo extract/pseudo raffinate recycle EXXON RESEARCH ENGINEERING CO (US) 1995-08-02 EP disclosed
US-5435918-A Aromatics and separation or settling, lubricants and raffinate EXXON RESEARCH & ENGINEERING CO. (US) 1995-07-25 US disclosed
EP-0421676-B1 Interfacially polymerized membranes, and reverse osmosis separation of organic solvent solutions using them EXXON RESEARCH ENGINEERING CO (US) 1994-11-30 EP disclosed
US-5234597-A Selective extraction of aromatic hydrocarbons from a mixture with non-aromatic hydrocarbons EXXON RESEARCH & ENGINEERING COMPANY (US) 1993-08-10 US disclosed
US-5182024-A SEPARATION OF HYDROCARBON DEWAXING AND DEASPHALTING SOLVENTS FROM DEWAXED AND/OR DEASPHALTED OIL USING INTERFACIALLY POLYMERIZED MEMBRANE EXXON RESEARCH AND ENGINEERING COMPANY (US) 1993-01-26 US disclosed
US-5173191-A INTERFACIALLY POLYMERIZED MEMBRANES FOR THE REVERSE OSMOSIS SEPARATION OF ORGANIC SOLVENT SOLUTIONS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1992-12-22 US disclosed
US-5128429-A Low temperature block polymerization without randomization RAYCHEM LIMITED (GB) 1992-07-07 US disclosed
EP-0421676-A1 Interfacially polymerized membranes, and reverse osmosis separation of organic solvent solutions using them EXXON RESEARCH AND ENGINEERING COMPANY (US) 1991-04-10 EP disclosed
US-4959405-A ACRYLATE, STRONG ORGANIC ACID ILLINOIS TOOL WORKS, INC. 1990-09-25 US disclosed
EP-0174045-B1 SEMIPERMEABLE COMPOSITE MEMBRANE STORK FRIESLAND B.V. (NL) 1988-08-03 EP disclosed
US-4721568-A VINYL AMINE-VINYL AMIDE CROSSLINKED WITH DIACID-CHLORIDE AND POLYAMINE WAFILIN B.V., (NL) 1988-01-26 US disclosed
EP-0251513-A2 Acid modified adhesive compositions ILLINOIS TOOL WORKS INC. (US) 1988-01-07 EP disclosed
US-4714730-A BONDING PLASTICS ILLINOIS TOOL WORKS INC. (US) 1987-12-22 US disclosed
EP-0174045-A1 Semipermeable composite membrane STORK FRIESLAND B.V. (NL) 1986-03-12 EP disclosed
EP-0053314-B1 PROCESS FOR THE CHLORO-SULPHONATION OF BIPHENYL AND DIPHENYL ETHER BAYER AG (DE) 1984-05-16 EP disclosed
EP-0053314-A1 Process for the chloro-sulphonation of biphenyl and diphenyl ether BAYER AG (DE) 1982-06-09 EP disclosed
US-4039440-A POLYETHYLENIMINE, ISOPHTHALOYL CHLORIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE INTERIOR (US) 1977-08-02 US disclosed