Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716561 | 0.90 | ALDH1A1 (0.39) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL13644404 | 0.87 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL13644405 | 0.87 | ALDH1A1 (0.43) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL14477876 | 0.87 | ALDH1A1 (0.41) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL18519479 | 0.84 | ALDH1A1 (0.41) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL12437264 | 0.82 | ALDH1A1 (0.42) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL7124340 | 0.82 | ALDH1A1 (0.46) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL4356827 | 0.82 | ALDH1A3 (0.46) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL7125837 | 0.82 | CYP2A6 (0.44) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E | |
| SCHEMBL18519480 | 0.81 | ALDH1A1 (0.37) | ALDH1A1ALDH1A3ALDH3A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| EP-3038621-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | Human Biomolecular Research Institute (US) | 2016-07-06 | — | — | EP | claimed |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2016-02-11 | — | — | US | claimed |
| WO-2014146039-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2014-09-18 | — | — | WO | claimed |
| CN-102250398-A | Polyolefin nucleating agent and preparation and application thereof | PETROCHINA CO LTD | 2011-11-23 | — | — | CN | claimed |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2023-03-07 | — | — | US | disclosed |
| EP-3498713-B1 | TRANSPARENT NUCLEATING AGENT COMPOSITION COMPRISING SORBITOL TRIACETALS AND MONOACETALS | GCH TECH CO LTD (CN) | 2022-01-05 | — | — | EP | disclosed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | disclosed |
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2020-12-29 | — | — | US | disclosed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3498713-A1 | TRANSPARENT NUCLEATING AGENT COMPOSITION COMPRISING SORBITOL TRIACETALS AND MONOACETALS | GCH Technology Co., Ltd. (CN) | 2019-06-19 | — | — | EP | disclosed |
| US-10208057-B2 | Nucleator composition comprising sorbitol acetal, sorbitol diacetal and sorbitol triacetal | GCH TECHNOLOGY CO., LTD. (CN) | 2019-02-19 | — | — | US | disclosed |
| CN-1238769-A | Sugar compounds, gelling agents, gelling agent compositions, processes for the preparation of them and gel compositions | NEW JAPAN CHEM CO LTD (JP) | 1999-12-15 | — | — | CN | disclosed |
| EP-0945452-A1 | SUGAR COMPOUNDS, GELLING AGENTS, GELLING AGENT COMPOSITIONS, PROCESSES FOR THE PREPARATION OF THEM, AND GEL COMPOSITIONS | NEW JAPAN CHEMICAL CO.,LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0647643-A1 | Bis(3,4-dialkylbenzylidene) sorbitol acetals and compositions containing same | MILLIKEN RESEARCH CORPORATION (US) | 1995-04-12 | — | — | EP | disclosed |
| US-5135975-A | Plastic additives useful as nucleating agents for food or cosmetic containers or packaging | MILLIKEN RESEARCH CORPORATION (US) | 1992-08-04 | — | — | US | disclosed |
| US-5049605-A | Nucleation, food or cosmetic packaging | MILLIKEN RESEARCH CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |
| EP-0421634-A2 | Use of bis(3,4-dialkylbenzylidene) sorbitol acetals and of compositions containing it | MILLIKEN RESEARCH CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| US-4188389-A | 1,2,3,4-Tetrahydropyrrolo(1,2-A)pyrazines | AYERST MCKENNA & HARRISON, INC. (CA) | 1980-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10874766-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | ALDH1A1 1461/4885ALDH1A3 1436/4885ALDH3A1 3489/4885 |
| US-11596716-B2 | Compounds and matrices for use in bone growth and repair | BMP2, BMP4, BMP6 | ALDH1A1 1413/4885ALDH1A3 1374/4885ALDH3A1 3103/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | ALDH1A1 1413/4885ALDH1A3 1374/4885ALDH3A1 3103/4885 |
| US-20160038641-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | ALDH1A1 1157/4885ALDH1A3 1049/4885ALDH3A1 3195/4885 |
| US-10208057-B2 | Nucleator composition comprising sorbitol acetal, sorbitol diacetal and sorbitol triacetal | SORD, DERA, SMCHD1 | ALDH1A1 1402/4885ALDH1A3 2888/4885ALDH3A1 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.